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检索条件"丛书名=IFIP Advances in Information and Communication Technology 461"

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Advancing ScRNA-Seq Data Integration via a Novel Gene Selection Method 1

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20th International Conference on Artificial Intelligence Applications and Innovations (AIAI)

作者： Lazaros, Konstantinos Exarchos, Themis Maglogiannis, Ilias Vlamos, Panagiotis Vrahatis, Aristidis G. Ionian Univ Dept Informat Bioinformat & Human Electrophysiol Lab Corfu 49100 Greece Univ Piraeus Dept Digital Syst Computat Biomed Lab Piraeus 18534 Greece

ISBN: (数字)9783031632112

ISBN: (纸本)9783031632136;9783031632112;9783031632105

Cancer presents a formidable challenge in medical research, spurring efforts to demystify its underlying mechanisms towards advancing precision medicine, which aims at tailoring treatments to individuals' genetic profiles. This study harnesses the power of single-cell RNA sequencing (scRNA-seq), a cutting-edge tool in next-generation sequencing, to delve into the transcriptomic intricacies of individual cells across diverse populations. Our methodology provides profound insights into gene expression patterns, significantly enhancing our understanding of cellular heterogeneity and its implications for cancer's pathogenesis. To address the 'curse of dimensionality' inherent in high-dimensional data, we introduce a sophisticated machine learning-based feature selection approach. This technique conceptualizes gene selection as a multi-label classification challenge, focusing on identifying genes critical for distinguishing between disease states and cell types. Importantly, our strategy underscores the value of data integration in reinforcing the statistical robustness of scRNA-seq analyses. By integrating disparate scRNA-seq datasets, we effectively mitigate batch effects, ensuring more accurate and reliable insights, thereby contributing significantly to the advancement of precision medicine in oncology.

关键词： scRNA-seq data integration batch effect multilabel classification

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Exploring Constrained-Modulus Modular Multipliers for Improved Area, Power and Flexibility 31st

Exploring Constrained-Modulus Modular Multipliers for Improv...

引用

31st International Conference on Very Large Scale Integration

作者： Nabee, Mohammed Soni, Deepraj Karri, Ramesh Maniatakosl, Michail New York Univ Abu Dhabi Abu Dhabi U Arab Emirates NYU New York NY USA

ISBN: (纸本)9783031709494;9783031709470;9783031709463

Fully Homomorphic Encryption (FHE) promises complete input privacy by allowing computation on encrypted data at the expense of high computation. FHE hardware accelerators improve performance with large and densely packed computing units, which could potentially create thermal hot spots because of high power consumption. Therefore, it is necessary to reduce the area and power consumption of the accelerator and its most critical module, i.e., the modular multiplier. In this work, we use the fact that, for FHE computation, the modulus should be of a specific form with its lower bits constrained to a decimal value of one. We examine the impact on area and power of two popular modular multiplication algorithms, Barrett and Montgomery, with different constrained widths for different modulus sizes. Our experiment results show that modular multipliers with constrained width can reduce area by 20% and power consumption by 15%-to-25%. We also propose an approximation for the number of prime moduli available with such a constrained modulus.

关键词： Modular Multiplier Montgomery Reduction Barrett Reduction Low-power design ASIC Design Fully Homomorphic Encryption

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Maturity Models for Servitization: A Systematic Literature Review 43rd

Maturity Models for Servitization: A Systematic Literature R...

引用

43rd ifip WG 5.7 International Conference on advances in Production Management Systems (APMS)

作者： Elena, Beducci de Carolis, Anna Taisch, Marco Politecn Milan Dept Management Econ & Ind Engn Via Lambruschini 4-B I-20156 Milan Italy

ISBN: (纸本)9783031716393;9783031716379;9783031716362

Servitization is the transition from selling products to selling integrated offerings of products and services. This trend is growing in the manufacturing context, being recognized as an opportunity to increase economic, environmental and social sustainability. To support companies in the transition towards servitization, Maturity Models represent a powerful tool to assess the maturity, strengths, and weaknesses and identify improvement activities. Existing literature proposes multiple maturity models for servitization and product service systems, with different focuses and structures. This paper aims to analyze the status of the existing literature on maturity models for servitization, identifying main characteristics, structures, trends, and gaps. To achieve this objective the paper operated a systematic literature review, including the identification and analysis of 19 contributions and 16 distinct maturity models. Based on the findings of the literature, the paper proposes categories of analysis that should be considered while assessing the maturity of companies involved in the servitization transition. This paper contributes to existing literature on servitization, it proposes an analysis of existing maturity models and rationalizes elements of analysis that should be taken into consideration in future works for the development of new maturity models.

关键词： Servitization Product Service System Maturity Model Systematic literature review

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Participation as Fuel for Transformation - An Approach to the Interrelations Between Digitalization, Participation and Values in NPOs 25th

Participation as Fuel for Transformation - An Approach to th...

引用

25th ifip WG 5.5 Working Conference on Virtual Enterprises (PRO-VE)

作者： Friedrich, Julia Roemer, Vanita Zinke-Wehlmann, Christian Inst Appl Informat Goerdelerring 9 D-04109 Leipzig Germany

ISBN: (纸本)9783031717413;9783031717390;9783031717383

Non-profit organizations (NPOs) differ from profit-oriented organizations not only in their motivation but also in their internal organizational structures as well as in their network embedding. In the implementation of digital structures within an NPO's very commonly, managerial methods that were developed for for profit organizations, are applied because of the lack of suitable alternatives. Yet, it is important to respect the organizational and motivational differences, as they have a crucial impact on the success of digital transformation processes. This paper wants to explore the state-of-the-art, both practical and theoretical, how digitalization transformation and organizational value can be brought together and be assessed by a participative approach, and how this can be a success factor in the development of the organization. The research is based on a mixed-methods approach that includes a literature review and an expert workshop with practitioners.

关键词： Digital Transformation Participation Organizational Values Non-Profit Organization

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Development of Automated Negotiation Models for Suppliers Using Reinforcement Learning 43rd

Development of Automated Negotiation Models for Suppliers Us...

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43rd ifip WG 5.7 International Conference on advances in Production Management Systems (APMS)

作者： Lee, Ga Hyun Song, Byunghun Jung, Jieun Jeon, Hyun Woo Kyung Hee Univ Dept Ind & Management Syst Engn Yongin Gyeonggi Do South Korea Korea Elect Technol Inst Smart Mfg Innovat Ctr Seongnam Si Gyeonggi Do South Korea

ISBN: (纸本)9783031716393;9783031716379;9783031716362

During a negotiating process in the supply chain, the negotiating parties try to maximize their interests while presenting a reasonable proposal that the counterpart may accept. Human negotiators, however, can have difficulties in making the optimal negotiation proposal or decision due to various limitations related to time, cost, and information processing capabilities. To deal with these issues, this study proposes artificial intelligence-based models to automate the negotiation process for a supplier in the supply chain. Specifically, we focus on the sell-side perspective as this area has not been studied comprehensively. To deal with the insufficient amount of data, we generate data on quantity (Q), price (P), and delivery lead time (D) by analyzing the correlation among these three variables from the available real transaction data. Then, more than 23,000 negotiation episodes between a buyer and a seller are simulated with correlated Q, P, and D. For learning the optimal negotiating strategy through simulated episodes, we apply the reinforcement learning models based on the Q-learning algorithm. We present two negotiation models: (i) a P negotiation model dependent on Q and (ii) a P negotiation model dependent on D. Our results show that the proposed structure of the automated negotiation model with correlated Q, P, and D can be applied to various negotiation environments by helping sell-side agents.

关键词： Automated Negotiation Simulation Data Generation Reinforcement Learning Q-learning

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A Study on Sophisticated Production Management for Engineer-to-Order Production: A Mixed Integer Programming Formulation for Production Scheduling 43rd

A Study on Sophisticated Production Management for Engineer-...

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43rd ifip WG 5.7 International Conference on advances in Production Management Systems (APMS)

作者： Morinaga, Eiji Iwamura, Koji Hirahara, Yoshiyuki Fukuda, Masamitsu Niinuma, Ayumu Oshima, Hirotomo Namioka, Yasuo Osaka Metropolitan Univ Sakai Osaka 5998531 Japan Toshiba Co Ltd Yokohama Kanagawa 2350017 Japan Adv Inst Ind Technol Shinagawa Ku Tokyo 1400011 Japan

ISBN: (纸本)9783031658969;9783031658945;9783031658938

Engineer-to-order (ETO) production in which products are designed and manufactured in response to customer orders is required to respond flexibly to customer requests at various stages from design to maintenance. This characteristic makes it difficult to apply a standard production planning strategy which divides the planning into three phases, i.e., long-term, medium-term and short-term planning (production scheduling), because there are large discrepancies among the phases and rescheduling requires a lot of man-hours. We proposed a production planning framework that unifies the granularity of resources and unit time in all of the planning phases aiming to reduce the discrepancies, and a model that is commonly used in the three phases of planning was organized as flexible job-shops. This paper provides a mixed integer programming formulation of the production scheduling problem based on the model considering the following characteristics of the target ETO production site: (1) The planner has discretion in shortening required processing time;(2) Operation time is limited to day time of weekdays;(3) Overtime works can be accepted if necessary;(4) Some operations of multiple parts must be processed at the same time on the same machine. A numerical experiment showed validity of the model.

关键词： Flexible job-shops Production scheduling Field-oriented method Mixed integer programming Engineer-to-order production

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The Culture and Climate for Agile Lean Thinking 9th

The Culture and Climate for Agile Lean Thinking

引用

9th European Lean Educator Conference on Challenging the Future with Lean (ELEC)

作者： Nelson, Stuart McDermott, Olivia Univ Galway Coll Sci & Engn Galway Ireland

ISBN: (纸本)9783031632679;9783031632655;9783031632648

The study aimed to investigate the impact of leadership style and psychological Safety on employee engagement. It further examined whether these variables differed in organisations that carried out initiatives such as Lean or Agile and their impact on the program's success. A self-selecting sample (N = 122) completed a series of questions, including the Multifactor Leadership Questionnaire Rater, the Utrecht Work Engagement Scale and Team Learning Psychological Safety instruments, and demographic information. A mixed design was used, part correlational and part cross-sectional. Results found that Transformational leadership style and Psychological Safety predicted Employee Engagement and that Quality Initiative organisations scored significantly higher on Transformational Leadership, Psychological Safety and Engagement. These factors also predicted the success of the Quality Initiative. This research demonstrated the importance of transformational Leadership and a psychologically safe environment to improve Engagement and that both can be learned.

关键词： Leadership Transformational Leadership Engagement Psychological Safety

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Utilizing Natural Language Processing for Enhancing Collaborative Value-Driven Design of Smart Product Service System: Smart E-Vehicle Application 25th

Utilizing Natural Language Processing for Enhancing Collabor...

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25th ifip WG 5.5 Working Conference on Virtual Enterprises (PRO-VE)

作者： Zhang, Yan Larsson, Andreas Larsson, Tobias Tian, Wenchong Zhang, Lan Wang, Wei Blekinge Inst Technol Dept Mech Engn Karlskrona Sweden BIGMind Innovat Shanghai Peoples R China City Univ HongKong Sch Energy & Environm Hong Kong Peoples R China Volkswagen Grp Beijing Peoples R China

ISBN: (纸本)9783031717413;9783031717390;9783031717383

Manufacturing companies are increasingly transitioning from a product-centric to a smart Product Service System (smart PSS) approach to enhance customer satisfaction, service offerings, and product competitiveness through a combination of usage scenarios and digital components. In the context of Industry 5.0 transformation such as developing the Smart Electric Vehicle (SEV), the automotive industry faces the challenge of understanding customers' descriptions of usage scenarios and translating the qualitative aspects of these scenarios into quantitatively assessed product features for collaborative value co-creation in smart PSS design. This paper addresses this challenge through utilizing Natural Language Processing (NLP) joint with Value-Driven Design (VDD) method for successfully supported a collaborative value exploration of in the smart PSS design stage. A case study was collaborated with a global automotive Original Equipment Manufacturer (OEM), Volkswagen, through proposing a NLP BERT model for VDD of Smart Electric Vehicle (SEV) design. Validation activities were performed by deploying the developed BERT model to the case company based on the scenario design of new car models.

关键词： Smart Product Service System Value-Driven Design Natural Language Processing Scenario Case

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Designing a New Dry Port-Seaport Logistics Network with a Focus on Industry 5.0 by Machine Learning 43rd

Designing a New Dry Port-Seaport Logistics Network with a Fo...

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43rd ifip WG 5.7 International Conference on advances in Production Management Systems (APMS)

作者： Rekabi, Shabnam Sazvar, Zeinab Dolgui, Alexandre Tavakkoli-Moghaddam, Reza Univ Tehran Coll Engn Sch Ind Engn Tehran Iran IMT Atlantique LS2N CNRS Nantes France

ISBN: (纸本)9783031716317;9783031716294;9783031716287

Dry Ports (DPs) are essential inland terminals that cover a variety of goods and are strategically established in several countries. According to the general structure of DPs across various countries, they play a major role in the field of multimodal transportation. Considering that some countries have wide beaches, they can earn non-oil income by using these beaches. Therefore, in this study, we are looking at the design of the Logistics Network (LN) for Dry Port-Seaports (DPSs), with an emphasis on multimodal transportation systems, by predicting demand utilizing a Machine Learning (ML) algorithm named Seasonal Autoregressive Integrated Moving Average (SARIMA). The mathematical model of this study includes three Objective Functions (OFs) (e.g., minimization of cost and environmental impact, and maximization of job opportunity and resilience). This work offers a mixed-integer programming model for setting up a viable LN by the Industry 5.0 (I5.0) dimension. Moreover, the Lp-metric, Goal Programming (GP), and Meta-GP (MGP) approaches are used to solve the developed model. Eventually, several quantitative illustrations are employed to evaluate the mentioned solution approach.

关键词： Dry Port-Seaport logistics Multi-modal transportation Industry5.0 Machine learning

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Pick-and-Place Robotics Implementation Under the Influence of Lean Manufacturing - A Process Model 43rd

Pick-and-Place Robotics Implementation Under the Influence o...

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43rd ifip WG 5.7 International Conference on advances in Production Management Systems (APMS)

作者： Rossini, Matteo Kassem, Bassel Narayanamurthy, Gopalakrishnan Staudacher, Alberto Portioli Politecn Milan Dept Management Econ & Ind Engn Milan Italy Amer Univ Emirates Coll Business Adm Dubai U Arab Emirates Univ Liverpool Management Sch Liverpool Merseyside England

ISBN: (纸本)9783031716317;9783031716294;9783031716287

The article seeks to develop a process model to guide research and practice in the effective integration of robotics for pick-and-place activities in manufacturing firms, where lean management tools and practices are being embraced. Utilizing a multiple case study analysis, the researchers conducted on-site visits to production facilities and analyzed 16 diverse projects, 11 coming from manufacturing companies and 5 projects provided by System Integrators, to gain heterogeneous and wide-spanning insights. The unit of analysis is the single robotic implementation, spanning across various sectors to extract patterns independently from the specific industry. These projects yielded a substantial volume of information, knowledge, and best practices related to the adoption of Robotics. Following a meticulous examination of the case studies, a process model was formulated to guide companies through decision-making, implementation, monitoring, and sustain stages in robotics introduction projects. This research disentangles the influence of lean management in ensuring the optimization of benefits derived from such projects. The process model seeks to offer practical guidance for companies approaching the complexities of robotics integration within manufacturing processes, successfully filling in the pre-existing research gap.

关键词： Robotics Industry 4.0 Lean implementation Process model

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