Genomics in Drug Discovery and Development

版本说明：1

作     者：Dimitri Semizarov Ph.D. Eric Blomme D.V.M., Ph.D. 

I S B N：(纸本) 9780470096048 

出 版 社：John Wiley & Sons  Inc. 

出 版 年：2008年

主 题 词：drug toxicity drug efficacy pharmaceutical R&D pharmaceuticals preclinical drug safety personal medicine genetic therapy genomics proteomics microarray data analysis toxicogenomics 

学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

摘      要：Early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure. By describing the available platforms and weighing their relative advantages and disadvantages, including microarray data analysis, Genomics in Drug Discovery and Development introduces readers to the biomarker, pharmacogenomic, and toxicogenomics toolbox. The authors provide a valuable resource for pharmaceutical discovery scientists, preclinical drug safety department personnel, regulatory personnel, discovery toxicologists, and safety scientists, drug development professionals, and pharmaceutical scientists.