Consensus on nomenclature for clinical staging models in bipolar disorder: A narrative review from the International Society for Bipolar Disorders (ISBD) Staging Task Force

作     者：Kupka, Ralph Duffy, Anne Scott, Jan Almeida, Jorge Balanza-Martinez, Vicent Birmaher, Boris Bond, David J. Brietzke, Elisa Chendo, Ines Frey, Benicio N. Grande, Iria Hafeman, Danella Hajek, Tomas Hillegers, Manon Kauer-Sant'Anna, Marcia Mansur, Rodrigo B. van der Markt, Afra Post, Robert Tohen, Mauricio Tremain, Hailey Vazquez, Gustavo Vieta, Eduard Yatham, Lakshmi N. Berk, Michael Alda, Martin Kapczinski, Flavio 

作者机构：Vrije Univ Dept Psychiat Amsterdam UMC Amsterdam Publ Mental HlthRes Inst Oldenaller 1 NL-1081 HJ Amsterdam Netherlands Queens Univ Cote Sharp Student Wellness Ctr Dept Psychiat Div Student Mental Hlth Kingston ON Canada Univ Oxford Dept Psychiat Oxford England Newcastle Univ Inst Neurosci Newcastle Upon Tyne Tyne & Wear England Univ Sydney Brain & Mind Ctr Sydney NSW Australia Univ Texas Austin Dell Med Sch Dept Psychiat & Behav Sci Austin TX USA Univ Valencia Dept Med Teaching Unit Psychiat & Psychol Med CIBERSAM Valencia Spain Univ Pittsburgh Med Ctr Pittsburgh PA USA Univ Minnesota Dept Psychiat & Behav Sci Sch Med Minneapolis MN USA Queens Univ Dept Psychiat Sch Med Kingston ON Canada Queens Univ Ctr Neurosci Studies Kingston ON Canada Hosp Santa Maria Psychiat Dept Dept Neurosci Lisbon Portugal Univ Lisbon Clin Univ Psiquiatria Fac Med Lisbon Portugal McMaster Univ Dept Psychiat & Behav Neurosci Hamilton ON Canada St Josephs Healthcare Hamilton Mood Disorders Program & Womens Hlth Concerns Cli Hamilton ON Canada Univ Barcelona Hosp Clin Inst Neurosci IDIBAPSCIBERSAMBarcelona Bipolar Disorders & De Barcelona Spain Univ Pittsburgh Sch Med Dept Psychiat Pittsburgh PA USA Dalhousie Univ Dept Psychiat Halifax NS Canada Erasmus MC Dept Child & Adolescent Psychiat Psychol Sophia Childrens Hosp Rotterdam Netherlands Univ Fed Rio Grande Sul UFRGS Hosp Clin Porto Alegre HCPA Fac Med Dept Psychiat Porto Alegre RS Brazil Univ Hlth Network Mood Disorders Psychopharmacol Unit Toronto ON Canada Univ Toronto Dept Psychiat Toronto ON Canada George Washington Univ Sch Med Washington DC USA Bipolar Collaborat Network Bethesda MD USA Univ New Mexico Dept Psychiat & Behav Sci Hlth Sci Ctr Albuquerque NM USA Swinburne Univ Fac Hlth Arts & Design Ctr Mental Hlth Melbourne Vic Australia Natl Ctr Excellence Youth Mental Hlth Orygen Parkville Vic Australia Queens Univ Dept Psychiat Kingston ON Canada Univ Barcelona Hosp Clin Inst Neurosci CIBERSAMIDIBAPS Barcelona Spain Univ British Columbia Dept Psychiat Vancouver BC Canada Deakin Univ Sch Med IMPACT Inst Mental & Phys Hlth & Clin Translat Barwon Hlth Geelong Vic Australia Univ Melbourne Natl Ctr Excellence Youth Mental Hlth Ctr Youth Mental HlthDept Psychiat Florey Inst Neurosci & Mental HlthOrygen Melbourne Vic Australia Dalhousie Univ Dept Psychiat Mood Disorders Clin Halifax NS Canada McMaster Univ St Josephs Healthcare Hamilton Hamilton ON Canada Univ Fed Rio Grande do Sul UFRGS Porto Alegre RS Brazil 

出 版 物：《BIPOLAR DISORDERS》 (双极混乱)

年 卷 期：2021年第23卷第7期

页      面：659-678页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 10[医学] 

基　　金：Angelini Pharma South Eastern Ontario Medical Association Lundbeck Merck H. Lundbeck A/S Merck ISCIII‐Subdirección General de Evaluación Meat and Livestock Board Cooperative Research Centre Cancer Council Victoria Otsuka Pharmaceutical Development and Commercialization, OPDC National Institute of Mental Health, NIMH AbbVie DSP Harry Windsor Foundation Department of Psychiatry and Centre for Neuroscience Studies Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES National Institutes of Health, NIH de Catalunya Fundação de Amparo à Pesquisa do Estado de São Paulo, FAPESP Harry Botterell Foundation for Neurological Sciences Medical Research Futures Fund Queen's University Otsuka Plan Nacional de I+D+I Janssen Research Foundation Simons Autism Foundation Servier Sanofi Pfizer European Regional Development Fund, ERDF Stanley Medical Research Foundation ZonMw, (60‐63600‐98‐021) Instituto de Salud Carlos III, ISCIII, (PI16/1770) Ministerio de Economía y Competitividad, MINECO, (PI19/00954, PI16/00187) Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO, (9120818) Ministerio de Ciencia e Innovación, MICINN, (PI15/00283, PI18/00805) AstraZeneca, (2017SGR1365) Departament de Salut, Generalitat de Catalunya, (SLT006/17/00357) Canadian Institutes of Health Research, CIHR, (142255, 106469, 103703) Brain and Behavior Research Foundation, BBRF, (20244) National Health and Medical Research Council, NHMRC, (1156072, 1059660) 

主　　题：bipolar disorders clinical staging nomenclature 

摘      要：Objectives Clinical staging is widely used in medicine to map disease progression, inform prognosis, and guide treatment decisions;in psychiatry, however, staging remains a hypothetical construct. To facilitate future research in bipolar disorders (BD), a well-defined nomenclature is needed, especially since diagnosis is often imprecise with blurred boundaries, and a full understanding of pathophysiology is lacking. Methods Under the auspices of the International Society of Bipolar Disorders, a Task Force of international experts was convened to review, discuss, and integrate findings from the scientific literature relevant to the development of a consensus staging model and standardize a terminology that could be used to advance future research including staging of BD and related disorders. Results Consensus opinion and areas of uncertainty or difference were identified in regard to terms referring to staging as it may apply to BD, to at-risk status and subthreshold stages, and to various clinical stages of BD as it is currently diagnosed. Conclusion The use of a standardized nomenclature about the clinical stages of BD will facilitate communication about research on clinical and pathological components of this heterogeneous group of disorders. The concepts presented are based on current evidence, but the template provided allows for further refinements as etiological advances come to light.