Dynamic radiomics: A new methodology to extract quantitative time-related features from tomographic images

作     者：Che, Fengying Shi, Ruichuan Li, Shuqin Wu, Jian Li, Haoran Chen, Weixing Zhang, Hao Qu, Hui Li, Zhi Cui, Xiaoyu 

作者机构：College of Medicine and Biological Information Engineering Northeastern University Liaoning Shenyang China Key Laboratory of Intelligent Computing in Medical Image Ministry of Education Key Laboratory of Data Analytics and Optimization for Smart Industry Northeastern University Liaoning Shenyang China Department of Medical Oncology The First Affiliated Hospital of China Medical University Liaoning110001 China Shenzhen College of Advanced Technology University of the Chinese Academy of Sciences Beijing100049 China Department of Breast Surgery Liaoning Cancer Hospital and Institute Cancer Hospital of China Medical University Liaoning Shenyang110042 China 

出 版 物：《arXiv》 (arXiv)

年 卷 期：2020年

核心收录：

主　　题：Tomography 

摘      要：The feature extraction methods of radiomics are mainly based on static tomographic images at a certain moment, while the occurrence and development of disease is a dynamic process that cannot be fully reflected by only static characteristics. This study proposes a new dynamic radiomics feature extraction workflow that uses time-dependent tomographic images of the same patient, focuses on the changes in image features over time, and then quantifies them as new dynamic features for diagnostic or prognostic evaluation. We first define the mathematical paradigm of dynamic radiomics and introduce three specific methods that can describe the transformation process of features over time. Three different clinical problems are used to validate the performance of the proposed dynamic feature with conventional 2D and 3D static *** results show that compared with static features, dynamic feature extraction can achieve higher robustness and accuracy for time-dependent tomographic images. We also found that the dynamic features that influence different clinical problems are also quite different. Copyright © 2020, The Authors. All rights reserved.