Wearable bioimpedance for continuous and context-aware clinical monitoring

作     者：Karlen, Walter Dutt, Abhilash Guru Verling, Michaela 

作者机构：Mobile Health Systems Lab Institute of Robotics and Intelligent Systems Department of Health Sciences and Technology ETH Zurich Zurich Switzerland 

出 版 物：《TechRxiv》 (TechRxiv)

年 卷 期：2020年

核心收录：

主　　题：Accelerometers 

摘      要：Bioimpedance monitoring provides a non-invasive, safe and affordable opportunity to monitor total body water for a wide range of clinical applications. However, the measurement is susceptible to variations in posture and movement. Existing devices do not account for these variations and are therefore unsuitable to perform continuous measurements to depict trend changes. We developed a wearable bioimpedance monitoring system with embedded real-time posture detection using a distributed accelerometer network. We tested the device on 14 healthy volunteers following a standardized protocol of posture change and evaluated the agreement with a commercial device. The impedance showed a high correlation (r0.98), a bias of -4.5 Ω, and limits of agreement of -30 and 21 Ω. Context-awareness was achieved with an accuracy of 94.6% by classifying data from two accelerometers placed at the upper and lower leg. The calculated current consumption of the system was as low as 10 mA during continuous measurement operation, suggesting that the system can be used for continuous measurements over multiple days without charging. The proposed motion-aware design will enable the measurement of relevant bioimpedance parameters over long periods and support informed clinical decision making. © 2020, CC BY-NC-SA.