Will warmer summers increase the impact of UV filters on marine bivalves?

作     者：Bordalo, Diana Cuccaro, Alessia Meucci, Valentina De Marchi, Lucia Soares, Amadeu M. V. M. Pretti, Carlo Freitas, Rosa 

作者机构：Univ Aveiro Dept Biol P-3810193 Aveiro Portugal Univ Aveiro Ctr Environm & Marine Studies CESAM P-3810193 Aveiro Portugal Univ Pisa Dept Vet Sci I-56122 Pisa Italy Interuniv Consortium Marine Biol & Appl Ecol G Bac I-57128 Livorno Italy 

出 版 物：《SCIENCE OF THE TOTAL ENVIRONMENT》 (整体环境科学)

年 卷 期：2023年第872卷

页      面：162108页

核心收录：

学科分类：0830[工学-环境科学与工程（可授工学、理学、农学学位）] 08[工学] 

基　　金：National Funds through the Portuguese Science Foundation (Fundacao para a Ciencia e a Tecnologia, FCT) [PD/BD/150609/2020] FCT/MCTES [UIDP/50017/2020 + UIDB/50017/2020 + LA/P/0094/2020] 

主　　题：Butyl methoxydibenzoylmethane Mussels Emerging pollutants Warming Oxidative stress Antioxidant responses 

摘      要：Marine organisms are constantly exposed to multiple stressors including pollutants released into the environment, such as personal care products (PCPs), and climate change-derived factors, namely warming, which are aggravated by anthropogenic drivers and pose increasing pressure on coastal ecosystems. Avobenzone (AVO) is one of the most used ultraviolet (UV) filters in PCPs which have been increasingly used and, thereby, identified in aquatic environ-ments. However, data regarding the influence of warming on the impacts caused by AVO in bivalves is lacking. Mussels are considered good bioindicators thus being often employed in ecotoxicology studies. Hence, the present study aimed to evaluate the toxic effects of an environmentally relevant concentration of AVO (0.5 mu g/L) and warming (21 degrees C), act-ing alone or in combination, on sperm and adults of the Mediterranean mussel species Mytilus galloprovincialis, through in vitro and in vivo tests, respectively. AVO and warming effects were evaluated by assessing oxidative status, viability, genotoxicity, motility, and kinetics in sperm, together with the quantification of energy content, metabolic capacity, biological defence mechanisms, cellular damage, and neurotoxicity in adults. AVO induced genotoxicity and increased respiration rate in sperm while enhancing the biotransformation enzymes activity in adults. Exposure to warming led to an increase in respiration rate, ROS overproduction, cellular damage, and viability decrease in sperm whereas met-abolic capacity increased in adults. AVO combined with warming caused oxidative stress, cellular damage, genotoxic-ity, and decreased motility in sperm, while only antioxidant enzymes activity was enhanced in adults. Overall, the present study demonstrated that when acting in combination the effects of both stressors were more prominent. Fur-thermore, considering the multiple-stressor scenario tested, major toxic effects occurred in male gametes in compari-son to adu