Network prediction of surgical complication clusters:a prospective multicenter cohort study

作     者：Xiaochu Yu Peng Wu Zixing Wang Wei Han Yuguang Huang Shijie Xin Qiang Zhang Shengxiu Zhao Hong Sun Guanghua Lei Taiping Zhang Luwen Zhang Yubing Shen Wentao Gu Hongwei Li Jingmei Jiang Xiaochu Yu;Peng Wu;Zixing Wang;Wei Han;Yuguang Huang;Shijie Xin;Qiang Zhang;Shengxiu Zhao;Hong Sun;Guanghua Lei;Taiping Zhang;Luwen Zhang;Yubing Shen;Wentao Gu;Hongwei Li;Jingmei Jiang

作者机构：Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing100730China Institute of Basic Medical SciencesChinese Academy of Medical Sciences/School of Basic MedicinePeking Union Medical CollegeBeijing100005China The First Hospital of China Medical UniversityShenyang110001China Qinghai Provincial People’s HospitalXining810007China Xiangya Hospital of Central South UniversityChangsha410008China Research DepartmentPaodingAIBeijing100083China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2023年第66卷第7期

页      面：1636-1646页

核心收录：

学科分类：12[管理学] 1201[管理学-管理科学与工程(可授管理学、工学学位)] 1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 081104[工学-模式识别与智能系统] 08[工学] 0835[工学-软件工程] 0811[工学-控制科学与工程] 0812[工学-计算机科学与技术（可授工学、理学学位）] 10[医学] 

基　　金：supported by the National Health and Family Planning Commission of China(201402017) 

主　　题：surgical complication network system complication grading complication prediction complication management 

摘      要：Complicated relationships exist in both occurrence and progression of surgical complications,which are difficult to account for using a separate quantitative method such as prediction or *** of 51,030 surgical inpatients were collected from four academic/teaching hospitals in a prospective cohort study in *** relationship between preoperative factors,22 common complications,and death was *** input from 54 senior clinicians and following a Bayesian network approach,a complication grading,cluster-visualization,and prediction(GCP)system was designed to model pathways between grades of complication and preoperative risk factor *** the GCP system,there were 11 nodes representing six grades of complication and five preoperative risk factor clusters,and 32 arcs representing a direct *** critical targets were pinpointed on the *** status was a fundamental cause widely associated(7/32 arcs)with other risk factor clusters and *** Society of Anesthesiologists(ASA)score≥3 was directly dependent on all other risk factor clusters and influenced all severe *** III complications(mainly pneumonia)were directly dependent on4/5 risk factor clusters and affected all other grades of *** of grade,complication occurrence was more likely to increase the risk of other grades of complication than risk factor clusters.