The Mediating Effect of Resilience on the Relationship Between Symptom Burden and Anxiety/Depression Among Chinese Patients with Primary Liver Cancer After Liver Resection

作     者：Zhang, Xue Zhang, Haoran Zhang, Zonghao Fan, Hua Li, Shuwen 

作者机构：Anhui Med Univ Sch Nursing Hefei 230601 Anhui Peoples R China Univ Sci & Technol China Anhui Prov Hosp Dept Hepatobiliary Surg Affiliated Hosp 1 Hefei Anhui Peoples R China 

出 版 物：《PATIENT PREFERENCE AND ADHERENCE》 (病人参考和依从性)

年 卷 期：2023年第17卷

页      面：3033-3043页

核心收录：

学科分类：12[管理学] 1204[管理学-公共管理] 120402[管理学-社会医学与卫生事业管理(可授管理学、医学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 10[医学] 

基　　金：Nursing School of Anhui Medical University Qingmiao's Program [hlqm12023047] 

主　　题：anxiety depression liver cancer resilience surgery symptom burden 

摘      要：Purpose: Primary liver cancer (PLC) is a common cancer of the digestive system. Patients with PLC often experience a heavy symptom burden and along with a significant levels of anxiety and depression after liver resection. High levels of symptom burden can lead to increased anxiety and depression, whereas high levels of resilience can alleviate these conditions. Therefore, we aimed to explore the relationships among symptom burden, resilience, and anxiety/depression in Chinese patients with PLC after liver resection and to determine whether resilience mediates the relationship between symptom burden and anxiety/*** and Methods: A total of 223 postoperative PLC patients were recruited from two public hospitals in Anhui Province, China. All participants completed the MD Anderson Symptom Inventory (MDASI), Hospital Anxiety and Depression Scale (HADS), and Connor-Davidson Resilience Scale (CD-RISC). The mediating effect of resilience was estimated using the bootstrap method viaResults: The mean HADS score was 12.37 +/- 6.03 points in postoperative PLC patients. Among these patients, 78 (34.98%) had anxiety, and 64 (28.70%) had depression, as indicated by a subscale score = 8. Pearson correlation analysis revealed that anxiety/ depression was positively associated with symptom burden (p 0.05) and negatively associated with resilience (p 0.05). Furthermore, resilience partially mediated the relationship between symptom burden and anxiety/depression (beta = 0.04;95% confidence interval: 0.01-0.08). Conclusion: The levels of anxiety and depression in postoperative PLC patients should be decreased. Resilience partially mediated the relationship between symptom burden and anxiety/depression, but the indirect effect was much weaker than the direct effect of symptom burden on anxiety/depression. Consequently, rather than focusing primarily on resilience interventions, joint symptompsychological interventions focusing on symptoms should be considered for pat