Bioresponsive fluorescent probes active in the second near-infrared window

作     者：Yuqin Chen Jie Chen Baisong Chang 

作者机构：State Key Laboratory of Advanced Technology for Materials Synthesis and ProcessingWuhan University of TechnologyWuhanChina 

出 版 物：《iRADIOLOGY》 (融合影像学(英文))

年 卷 期：2023年第1卷第1期

页      面：36-60页

学科分类：08[工学] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

基　　金：Young Top-notch Talent Cultivation Program of Hubei Province,China Natural Science Foundation of Hubei Province,Grant/Award Number:2021CFB344 

主　　题：composite engineering second near-infrared window smart probe stimulus sensitivity pathophysiological microenvironment 

摘      要：Emerging stimuli-responsive composite probes active in the second nearinfrared window(NIR-II,1000–1700 nm)hold vast potential for improving in vivo imaging performance with minimized noise *** interactions among external irradiation,shell species,and the emissive core are key factors in the design of smart *** external irradiation provides energy for shell species and the emissive core to generate intense NIR-II fluorescence signals,while the energy transfer process hinders NIR-II emission in the inner structure of smart composite ***,if pathophysiological stimuli interrupt the above processes,then NIR-II fluorescence signals are *** review covers NIR-II imaging based on diverse smart composite NIR-II fluorescent probes responding to various biological stimuli,including ONOO−,overexpressed reactive sulfur species,abnormally expressed enzymes,and abnormal levels of physiological ***,to appreciate these advances,the challenges and perspectives of stimuliresponsive composite NIR-II probes are highlighted.