Cover Feature: Singlet Oxygen Oxidation of the Radical Cations of 8-Oxo-2′-deoxyguanosine and Its 9-Methyl Analogue: Dynamics, Potential Energy Surface, and Products Mediated by C5-O2-Addition (ChemPlusChem 9/2021)

作     者：May Myat Moe Prof. Dr. Midas Tsai Prof. Dr. Jianbo Liu 

作者机构：Department of Chemistry and Biochemistry Queens College of the City University of New York 65-30 Kissena Blvd. Queens NY 11367 USA Ph.D. Program in Chemistry The Graduate Center of the City University of New York 365 5th Ave. New York NY 10016 USA Department of Natural Sciences LaGuardia Community College 31-10 Thomson Ave. Long Island City NY 11101 USA 

出 版 物：《ChemPlusChem》 (化学化工杂志)

年 卷 期：2021年第86卷第9期

页      面：1226-1226页

学科分类：07[理学] 0703[理学-化学] 

主　　题：ion-molecule reaction mass spectrometry nucleosides reaction mechanisms singlet oxygen 

摘      要：The Cover Feature illustrates a synergetic damage of DNA guanine nucleobases by ionizing radiation and accompanying oxidation by electronically excited singlet molecular oxygen. These concurrent oxidative processes lead to prevalent DNA lesions in vivo. Their reaction mechanisms, dynamics, and product structures were revealed by gas-phase ion-molecule reactions and mass spectrometry, from which a molecular-level understanding of the chemistry is provided for elucidating the biological consequences and implications. Cover design by May Myat Moe. More information can be found in the Full Paper by J. Liu and co-workers.