Enhancing cellular behavior in repaired tissue via silk fibroin-integrated triboelectric nanogenerators

作     者：Zhelin Li Shuxing Xu Zijie Xu Sheng Shu Guanlin Liu Jianda Zhou Ding Lin Wei Tang 

作者机构：Changsha Aier Eye HospitalAier School of OphthalmologyCentral South UniversityChangshaHunanChina The Xiangya HospitalCentral South UniversityChangshaHunanChina Beijing Institute of Nanoenergy and NanosystemsChinese Academy of SciencesBeijing 101400China Center on Nanoenergy ResearchSchool of Physical Science&TechnologyGuangxi UniversityNanning 530004China School of Nanoscience and TechnologyUniversity of Chinese Academy of SciencesBeijing 100049China Department of Plastic Surgerythe Third Xiangya HospitalChangshaHunanChina 

出 版 物：《Microsystems & Nanoengineering》 (微系统与纳米工程（英文）)

年 卷 期：2024年第10卷第3期

页      面：137-147页

核心收录：

学科分类：080801[工学-电机与电器] 0808[工学-电气工程] 07[理学] 070205[理学-凝聚态物理] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0702[理学-物理学] 

基　　金：supported by the National Key Research and Development Program of China(No.2021YFA1201601) the National Natural Science Foundation of China(No.52192610) 

主　　题：overcome spite generating 

摘      要：Triboelectric nanogenerators(TENGs)have emerged as a promising approach for generating electricity and providing electrical stimuli in medical electronic *** their potential benefits,the clinical implementation of TENGs faces challenges such as skin compliance and a lack of comprehensive assessment regarding their biosafety and ***,further research is imperative to overcome these limitations and unlock the full potential of TENGs in various biomedical *** this study,we present a flexible silk fibroin-based triboelectric nanogenerator(SFB-TENG)that features an on-skin substrate and is characterized by excellent skin compliance and air/water *** range of electrical output generated by the SFB-TENG was shown to facilitate the migration and proliferation of Hy926,NIH-3T3 and RSC96 ***,apoptosis of fibroblast NIH-3T3 cells was observed when the output voltage increased to more than 20 V at a frequency of 2 *** addition,the moderate electrical stimulation provided by the SFB-TENG promoted the cell proliferation cycle in Hy926 *** research highlights the efficacy of a TENG system featuring a flexible and skin-friendly design,as well as its safe operating conditions for use in biomedical *** findings position TENGs as highly promising candidates for practical applications in the field of tissue regeneration.