Using the appropriate modulus of elasticity of periodontal ligament matters in stress analysis of human first premolar tooth and periodontium structures

作     者：Dhammayannarangsi, Phetcharat Lampang, Sorapon Na Tompkins, Kevin A. Everts, Vincent Osathanon, Thanaphum Limjeerajarus, Chalida Nakalekha Limjeerajarus, Nuttapol 

作者机构：Chulalongkorn Univ Fac Dent Grad Sch Dept Dent Biomat Sci Bangkok 10330 Thailand Chulalongkorn Univ Fac Dent Off Res Affairs Bangkok 10330 Thailand Univ Amsterdam Fac Dent Dept Oral Cell Biol Amsterdam Netherlands Vrije Univ Amsterdam Netherlands Chulalongkorn Univ Fac Dent Ctr Excellence Dent Stem Cell Biol Dept Anat Bangkok 10330 Thailand Chulalongkorn Univ Fac Dent Ctr Excellence Genom & Precis Dent Dept Physiol Henri Dunant Rd Bangkok 10330 Thailand 

出 版 物：《SCIENTIFIC REPORTS》 (Sci. Rep.)

年 卷 期：2025年第15卷第1期

页      面：1-17页

核心收录：

基　　金：Second Century Fund [C2F] Chulalongkorn University Dental Faculty Research [DRF67006] Faculty of Dentistry, Chulalongkorn University National Science, Research and Innovation Fund (NSRF) via the Program Management Unit for Human Resources & Institutional Development, Research and Innovation [B16F640118] 

主　　题：Modulus of elasticity Periodontal ligament Stress distribution Finite element analysis Multi-component model First premolar 

摘      要：Although the modulus of elasticity of the human periodontal ligament (EPDL) values used in dentistry widely ranged from 0.01 to 175 MPa, the exact EPDL value has not been determined. This study aimed to verify whether and how EPDL values affect the stress distribution over the tooth and periodontium structures, and to determine the appropriate EPDL range. A 3D multi-component human first premolar model was created based on a cone-beam computed tomography dataset. Finite element analysis was performed to analyze stress distribution and deformation of the structures under an average Asian occlusal force with different EPDL values (0.0689-68.9 MPa). The low EPDL caused excessive PDL deformation, contributing to a non-uniform stress distribution and localized stress concentration, especially in the cementum, enamel, and dentin. With the low EPDL value, the stress magnitude was overestimated by 1,195%, potentially leading to erroneous conclusions regarding material failure and tooth movement. The EPDL value significantly affects the stress magnitude and distribution over the tooth and periodontium. The appropriate EPDL range of 0.964 +/- 0.276 MPa is suggested for human first premolars to ensure accurate and reliable FEA simulations and help avoid misinterpretation of the stress results, which could compromise orthodontic planning and restoration design.