肠球菌尿路感染研究进展

作     者：刘子寒 张晓兵 

作者机构：重庆医科大学附属第一医院医学检验科重庆 

出 版 物：《临床医学进展》 (Advances in Clinical Medicine)

年 卷 期：2025年第15卷第1期

页      面：878-885页

学科分类：100208[医学-临床检验诊断学] 1002[医学-临床医学] 10[医学] 

主　　题：肠球菌 耐药情况 致病机制 肠球菌尿路感染 防治 

摘      要：肠球菌感染最常见的部位是泌尿道,尿路感染最常见的革兰阳性细菌为肠球菌。近年来,肠球菌因其在临床上的耐药性和致病性受到越来越多的关注,尤其是耐万古霉素肠球菌出现后,肠球菌成为引发感染的第二大病原体,同时也是重要的医院获得性感染病原体之一,给患者的生命带来了威胁,同时也给肠球菌尿路感染的临床治疗带来了挑战。本文就肠球菌的病原学特征、耐药性、致病机制、肠球菌尿路感染的临床特征以及防治手段进行综述。The urinary tract is the most prevalent site for enterococcal infections, and enterococci are the most frequently encountered Gram-positive bacteria responsible for urinary tract infections. In recent years, enterococci have garnered significant attention due to their clinical resistance and pathogenic potential, especially with the emergence of vancomycin-resistant Enterococci. Enterococci have become the second leading cause of infections, as well as one of the important pathogens of hospital-acquired infections, posing a threat to patients’ lives and challenging the clinical treatment of Enterococcal urinary tract infections. This article reviews the characteristics, resistance, pathogenic mechanisms of enterococci and characteristics of enterococcal urinary tract infections, and strategies for prevention and treatment.