Harnessing the enol/keto-form emission of ESIPT: mechanochromism, multi-channel imaging, and detection of a chemical warfare agent mimic

作     者：Kangmin Wang Min Zhang Danni Yang Liqiu Wan Shouxin Zhang Liang Yan Ke Yang Bijin Li 王康敏;张敏;杨丹妮;万立秋;张守鑫;颜亮;杨科;李必进

作者机构：Chongqing Key Laboratory of Natural Product Synthesis and Drug ResearchSchool of Pharmaceutical Sciences&Department of Medical LaboratoryShapingba Hospital Affiliated to Chongqing UniversityChongqing UniversityChongqing 401331China State Key Laboratory of NBC Protection for CivilianBeijing 100191China Jiangsu Key Laboratory of Advanced Catalytic Materials&TechnologySchool of Petrochemical EngineeringChangzhou UniversityChangzhou 213164China 

出 版 物：《Science China Materials》 (中国科学(材料科学)(英文版))

年 卷 期：2025年第68卷第2期

页      面：448-454页

核心收录：

学科分类：08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 

基　　金：supported by the Fundamental Research Funds for the Central Universities (2023CDJYGRH-YB17, 2024CDJXY002, 2024CDJQYJCYJ-001) the Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology (BM2012110) the Scientific and Technological Project of Jiangsu Province (BZ2023055, BE2023693) the Venture & Innovation Support Program for Chongqing Overseas Returnees (cx2022061) the Natural Science Foundation of Chongqing (CSTB2022NSCQ-MSX1123) the Chongqing Talents: Exceptional Young Talents Project (cstc2021ycjhbgzxm0067) Changzhou University, Advanced Catalysis and Green Manufacturing Collaborative Innovation Center (ACGM2022–10–10) the National Natural Science Foundation of China (21702019) 

主　　题：fluorescent materials enol-form emission keto-form emission ESIPT chemical warfare agents 

摘      要：Reported herein is the first time mechanochromicmaterials based on sole enol-form emission of 2-(2’-hydroxyphenyl)azoles containing one triphenylamine (TPA).Three different single crystals were obtained and representpristine, intermediate, and ground states, respectively. The 2-(2’-hydroxyphenyl)azoles containing two TPA exhibit balanced dual-emission and could be used in multi-channelimaging, and selectivity accumulated in mitochondria of livingcells. In addition, we developed the first example of excitedstate intramolecular proton transfer (ESIPT) materials withsole enol-form emission and balanced dual-emission to detectchemical warfare agents (CWAs) mimic diethyl chlorophosphate (DCP) with good selectivity, highly sensitive, and fastresponsive.