ALOE VERA-LOADED GELATIN METHACRYLOYL HYDROGELS AS POTENTIAL BONE BIOMATERIALS

作     者：Nicolae, Carmen-Valentina Iordache, Iulia-Maria Banciu, Adela Stancu, Izabela-Cristina 

作者机构：Dept. of Bioresources and Polymer Science Faculty of Chemical Engineering and Biotechnologies Advanced Polymer Materials Group National University of Science and Technology POLITEHNICA Bucharest Romania Smart Biomaterials and Applications Faculty of Medical Engineering National University of Science and Technology POLITEHNICA Bucharest Romania Faculty of Medical Engineering National University of Science and Technology POLITEHNICA Bucharest Romania 

出 版 物：《UPB Scientific Bulletin, Series B: Chemistry and Materials Science》 (UPB Sci Bull Ser B)

年 卷 期：2024年第86卷第4期

页      面：131-144页

核心收录：

基　　金：This work was supported from the project Integrating mechanically-tunable 3D printing with new bioactive multi(nano)materials for next functional personalized bone regenerative scaffolds  PN-III-P4-PCE-2021–1240  no. PCE 88/2022 

主　　题：Microgels 

摘      要：This study reports the development of gelatin methacryloyl (GelMA) hydrogels loaded with aloe vera (AV) compounds as potential biomaterials for bone tissue regeneration. By incorporating lyophilized AV gel and commercially available AV powder into GelMA hydrogels, we aimed to leverage the synergistic bioactivity of AV components for comprehensive tissue regeneration. The effect of AV compounds addition to the GelMA network was investigated through gel fraction evaluation and rheological measurements. The results suggest that the formulations could meet the standards for the targeted application, while their rheological, network-forming and antibacterial properties are significantly influenced by the incorporation of lyophilized AV gel. © 2024, Politechnica University of Bucharest. All rights reserved.