Sonopharmacology:Regulation of drug activity through ultrasound

作     者：Wenjing Zhang Fangyin Song Zhiyuan Shi Xin Li Kuailu Lin Wenjing Zhang;Fangyin Song;Zhiyuan Shi;Xin Li;Kuailu Lin

作者机构：Department of Breast SurgeryThe First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang325015China Collaborative Innovation Center of Yangtze River Delta Region Green PharmaceuticalsZhejiang University of TechnologyHangzhou310014China School of Pharmaceutical Science and TechnologyFaculty of MedicineTianjin UniversityTianjin300072China Department of Polymeric MaterialsSchool of Materials Science and EngineeringTongji UniversityShanghai201804China 

出 版 物：《Journal of Pharmaceutical Analysis》 (药物分析学报(英文版))

年 卷 期：2024年第14卷第12期

页      面：1732-1735页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：国家自然科学基金 the Shanghai Pujiang Program, China the Science and Technology Project of Wenzhou, China 

主　　题：photoswitches sonopharmacology bioactive substances drug activity light irradiationthe phototoxicity introduction photoswitches ultrasound 

摘      要：*** The introduction of photoswitches into the bioactive substances is the fundamental idea behind *** light irradiation,the drug activity can be spatiotemporally controlled by the photon-induced variety of photoswitch s structures or characteristics[1].However,some challenges are still faced in photopharmacology including phototoxicity and limited tissue penetration depth(about a few millimeters).