Evaluating the performance of the PREDAC method in flu vaccine recommendations over the past decade(2013-2023)

作     者：Yousong Peng Lei Yang Weijuan Huang Mi Liu Xiao Ding Xiangjun Du Yuelong Shu Taijiao Jiang Dayan Wang 

作者机构：Bioinformatics CenterCollege of BiologyHunan Provincial Key Laboratory of Medical VirologyHunan UniversityChangsha410082China National Institute for Viral Disease Control and PreventionChina CDCBeijing102206China Jiangsu Institute of Clinical ImmunologyThe First Affiliated Hospital of Soochow UniversitySuzhou215006China Suzhou Institute of Systems MedicineSuzhou215123China Department of Biostatistics and Systems BiologySchool of Public Health(Shenzhen)Sun Yat-sen UniversityShenzhenGuangdong510275China Key Laboratory of Pathogen Infection Prevention and Control(MOE)State Key Laboratory of Respiratory Health and MultimorbidityNational Institute of Pathogen BiologyChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing102629China Guangzhou National LaboratoryGuangzhou510005China 

出 版 物：《Virologica Sinica》 (中国病毒学(英文版))

年 卷 期：2025年第40卷第2期

页      面：288-291页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：upported by the Major Project of Guangzhou National Laboratory(GZNL2024A01002) National Key Plan for Scientific Research and Development of China(2022YFC2303802) National Natural Science Foundation of China(32170651&32370700) Hunan Provincial Natural Science Foundation of China(2024JJ2015) 

主　　题：antigenic variation influenza viruses update vaccine strains vaccination effectiveness influenza virus predac method monitor antigenic variation vaccine recommendations 

摘      要：Dear Editor,Influenza viruses cause significant mortality and morbidity in *** is currently the most effective way to combat the virus(Perofsky and Nelson,2020).Unfortunately,the influenza virus frequently changes its antigenicity through rapid mutations,leading to decreased vaccine efficacy or even *** improve vaccine effectiveness,it is necessary to monitor antigenic variation and update vaccine strains when significant antigenic variation occurs(Perofsky and Nelson,2020;Malik et al.,2024).