沙门氏菌耐药性的研究进展

作     者：杨君涵 张晓兵 

作者机构：重庆医科大学附属第一医院医学检验科重庆 

出 版 物：《临床医学进展》 (Advances in Clinical Medicine)

年 卷 期：2025年第15卷第1期

页      面：1639-1645页

学科分类：0906[农学-兽医学] 09[农学] 

主　　题：沙门氏菌 耐药性 多重耐药 耐药机制 

摘      要：沙门氏菌是最常见的食源性致病菌之一,对公共卫生构成了严重威胁。近年来沙门氏菌耐药性呈上升趋势,同时多重耐药菌株的增加也给临床治疗带来了巨大困难,这已成为全球公共卫生面临的一个重大挑战。本文综述了沙门氏菌的耐药机制、耐药性的分布和趋势,以及耐药性的防控策略,旨在增强对沙门氏菌耐药性问题的认识,为控制感染、防止耐药菌的传播以及制定合适的治疗方案提供科学依据。Salmonella is one of the most common foodborne pathogens, posing a severe threat to public health. In recent years, the antimicrobial resistance of Salmonella has been increasing, and the rise in multidrug-resistant strains has also posed significant challenges to clinical treatment. This has become a major challenge facing global public health. This article reviews the mechanisms of drug resistance in Salmonella, the distribution and trends of antimicrobial resistance, and strategies for the prevention and control of antimicrobial resistance in salmonella. It aims to enhance the understanding of the issue of Salmonella resistance and provide a scientific basis for controlling infections, preventing the spread of resistant strains, and developing appropriate treatment plans.