小儿胃食管反流病诊断最新进展

作     者：贺小宝 权乔莉 李元霞 

作者机构：延安大学医学院陕西 延安 空军军医大学第一附属医院西京医院门诊部陕西 延安 

出 版 物：《临床医学进展》 (Advances in Clinical Medicine)

年 卷 期：2025年第15卷第2期

页      面：1177-1182页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：胃食管反流病 诊断 检查方法 

摘      要：胃食管反流病是由反流引起的具有临床表现的综合征,是儿科常见的上消化道动力障碍性疾病,该病的诊断主要依靠临床症状和相关检查综合判断,婴儿期临床表现多种多样,GERD严重时导致生长发育落后,甚至死亡,临床诊断困难,且国内尚缺乏诊断该疾病金标准,各医院之间诊断病例差异极大,本文介绍了食管pH检测,食管阻抗-pH监测,内窥镜检查和活检,唾液胃蛋白酶测量,钡餐检查,超声检查和质子泵抑制试验这些检查在诊断该疾病的最新研究进展。Gastroesophageal reflux disease (GERD) is a syndrome with clinical manifestations caused by reflux, and it is a common upper gastrointestinal tract dysfunctional disease in pediatrics. The diagnosis of this disease mainly relies on the comprehensive judgment of clinical symptoms and related examinations, and the clinical manifestations are various in infancy, and GERD leads to growth retardation and even death in severe cases, which is difficult to diagnose clinically, and the gold standard for diagnosing this disease is still lacking in China, and the diagnosis varies among hospitals. This paper introduces the latest research progress of esophageal pH test, esophageal impedance-PH monitoring, endoscopy and biopsy, salivary pepsin measurement, barium meal examination, ultrasonography and proton pump inhibition test in the diagnosis of this disease.