Research progress and prospects of experimental murine behavior evaluation methods

作     者：Chen Du Ying Wang Ziyi Li Ziyan Wu Dingyuan Liang Yuliang Zhao Jin Zhou Yubo Fan 

作者机构：Key Laboratory of Biomechanics and Mechanobiology (Beihang University) Ministry of Education Key Laboratory of Innovation and Transformation of Advanced Medical Devices Ministry of Industry and Information Technology National Medical Innovation Platform for Industry-Education Integration in Advanced Medical Devices (Interdiscipline of Medicine and Engineering) School of Biological Science and Medical Engineering Beihang University 100191 Beijing China Department of Mechanical Engineering City University of Hong Kong 999077 Hong Kong Special Administrative Region of China School of Control Engineering Northeastern University at Qinhuangdao Qinhuangdao 066004 Hebei China 

出 版 物：《Medicine in Novel Technology and Devices》 (Med. Novel Tech. Dev.)

年 卷 期：2025年第27卷

基　　金：National Health Commission of the People's Republic of China, NHC Natural Science Foundation of Beijing Municipality, (7232339) Natural Science Foundation of Beijing Municipality Zhejiang Provincial Major Science and Technology Plan Project of Medicine and Health, (WKJ-ZJ-2412) 

主　　题：Murine behaviors Behavioral tracking Behavior evaluation method Technological advancements 

摘      要：Experimental murine behaviors, including communication, emotional expression, social interaction, learning, and reproduction, play a critical role in various research fields such as genetics, neuroscience, and non-neuroscience disciplines. The growing demand for murine behavior research has driven the development of diverse evaluation methods. Current evaluation techniques include assessments based on ordinary or high-speed cameras, active depth sensors, inertial sensors, optical pressure plates, electromyography, and two-photon fluorescence microscopy. Each method has its unique advantages and limitations depending on the experimental context. Therefore, selecting an appropriate evaluation method tailored to specific experimental requirements is crucial for obtaining accurate and meaningful results. This review summarizes the advancements in experimental murine behavior evaluation methods over the past decade, providing a comprehensive overview of their applications and contributions to behavioral research.