Fibonacci Sequence and Supramolecular Structure of DNA

作     者：Shabalkin, I. P. Grigor'eva, E. Yu. Gudkova, M. V. Shabalkin, P. I. 

作者机构：NN Blokhin Russian Canc Res Ctr Moscow Russia 

出 版 物：《BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE》 (实验生物学与医学通报)

年 卷 期：2016年第161卷第1期

页      面：193-196页

核心收录：

学科分类：0710[理学-生物学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 09[农学] 

主　　题：monomers supramolecular structure DNA Fibonacci sequence 

摘      要：We proposed a new model of supramolecular DNA structure. Similar to the previously developed by us model of primary DNA structure [11-15], 3D structure of DNA molecule is assembled in accordance to a mathematic rule known as Fibonacci sequence. Unlike primary DNA structure, supramolecular 3D structure is assembled from complex moieties including a regular tetrahedron and a regular octahedron consisting of monomers, elements of the primary DNA structure. The moieties of the supramolecular DNA structure forming fragments of regular spatial lattice are bound via linker (joint) sequences of the DNA chain. The lattice perceives and transmits information signals over a considerable distance without acoustic aberrations. Linker sequences expand conformational space between lattice segments allowing their sliding relative to each other under the action of external forces. In this case, sliding is provided by stretching of the stacked linker sequences.