Accurate prediction of V1 location from cortical folds in a surface coordinate system

作     者：Hinds, Oliver P. Rajendran, Niranjini Polimeni, Jonathan R. Augustinack, Jean C. Wiggins, Graham Wald, Lawrence. L. Rosas, H. Diana Potthast, Andreas Schwartz, Eric L. Fischl, Bruce 

作者机构：Boston Univ Dept Cognit & Neural Syst Boston MA 02215 USA Harvard Univ Sch Med MGH Dept RadiolAthinoula A Martinos Ctr Cambridge MA 02138 USA Harvard Univ Sch Med MGH Dept NeurolAthinoula A Martinos Ctr Cambridge MA 02138 USA Siemens Med Solut Inc Malvern PA USA Boston Univ Dept Elect & Comp Engn Boston MA 02215 USA Boston Univ Sch Med Dept Anat & Neurobiol Boston MA 02215 USA MIT Comp Sci & Artificial Intelligence Lab Cambridge MA 02139 USA 

出 版 物：《NEUROIMAGE》 (神经图像)

年 卷 期：2008年第39卷第4期

页      面：1585-1599页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 1010[医学-医学技术（可授医学、理学学位）] 1009[医学-特种医学] 10[医学] 

基　　金：NCRR NIH HHS [R01 RR 16594, U24 RR 021382, P41 RR 14075] Funding Source: Medline NIA NIH HHS [P50 AG 005134, 5 P50 AG 05134] Funding Source: Medline NIBIB NIH HHS [R01 EB 001550, U54 EB 005149, R01 EB001550-01] Funding Source: Medline NINDS NIH HHS [R01 NS 052585] Funding Source: Medline 

主　　题：Aged Algorithms Autopsy Autopsy Cerebral Cortex/anatomy & histology Female Functional Laterality/physiology Humans Image Processing, Computer-Assisted/methods Image Processing, Computer-Assisted/statistics & numerical data Magnetic Resonance Imaging Male Middle Aged Models, Statistical Predictive Value of Tests Stereotaxic Techniques Visual Cortex/anatomy & histology 

摘      要：Previous studies demonstrated substantial variability of the location of primary visual cortex (V1) in stereotaxic coordinates when linear volume-based registration is used to match volumetric image intensities [Amunts, K., Malikovic, A., Mohlberg, H., Schormann, T., and Zilles, K. (2000). Brodmann s areas 17 and 18 brought into stereotaxic space-where and how variable? Neurohnage, 11(1):66-84]. However, other qualitative reports of V1 location [Smith, G. (1904). The morphoiogy of the occipital region of the cerebral hemisphere in man and the apes. Anatomischer Anzeiger, 24:436-451;Stensaas, S.S., Eddington, D.K., and Dobelle, W.H. (1974). The topography and variability of the primary visual cortex in man. J Neurosurg, 40(6):747-755;Rademacher, J., Caviness, V.S., Steinmetz, H., and Galaburda, A.M. (1993). Topographical variation of the human primary cortices: implications for neuroimaging, brain mapping, and neurobiology. Cereb Cortex, 3 (4):313-329] suggested a consistent relationship between V1 and the surrounding cortical folds. Here, the relationship between folds and the location of V1 is quantified using surface-based analysis to generate a probabilistic atlas of human V1. High-resolution (about 200 pm) magnetic resonance imaging (MRI) at 7 T of ex vivo human cerebral hemispheres allowed identification of the full area via the stria of Gennari: a myeloarchitectonic feature specific to V1. Separate, whole-brain scans were acquired using MRI at 1.5 T to allow segmentation and mesh reconstruction of the cortical gray matter. For each individual, V1 was manually identified in the high-resolution volume and projected onto the cortical surface. Surface-based intersubject registration [Fischl, B., Screno, M.I., Tootell, R.B., and Dale, A.M. (1999b). High-resolution intersubject averaging and a coordinate system for the cortical surface. Haiti Brain Mapp, 8(4):272-84] was performed to align the primary cortical folds of individual hemispheres to those of a reference