Risk factors for liver disease among adults of Mexican descent in the United States and Mexico

作     者：Yvonne N Flores Zuo-Feng Zhang Roshan Bastani Mei Leng Catherine M Crespi Paula Ramírez-Palacios Heather Stevens Jorge Salmerón 

作者机构：Unidad de Investigación Epidemiológica y en Servicios de SaludDelegación MorelosInstituto Mexicano del Seguro SocialCuernavacaMorelos 62000México UCLA Department of Health Policy and Management and Kaiser Permanente Center for Health EquityFielding School of Public HealthLos AngelesCA 90095United States UCLA Cancer Prevention and Control Research CenterFielding School of Public Health and Jonsson Comprehensive Cancer CenterLos AngelesCA 90095United States UCLA Division of General Internal Medicine and Health Services ResearchLos AngelesCA 90095United States UCLA Department of BiostatisticsFielding School of Public HealthLos AngelesCA 90095United States University of WashingtonSchool of MedicineSeattleWA 98195United States Universidad Nacional Autónoma de MéxicoAcademic Epidemiology Research UnitAvenida Universidad 3000Ciudad UniversitariaCoyoacánMexico City 04510México Centro de Investigación en Salud PoblacionalInstituto Nacional de Salud PúblicaCuernavacaMorelos 62100México 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2018年第24卷第37期

页      面：4281-4290页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by the Programa de Investigación en Migracion y Salud(PIMSA),No.2015-2106 the Instituto Mexicano del Seguro Social(IMSS),No.2005/1/Ⅰ/093 and the Consejo Nacional de Ciencia y Tecnología(CONACYT),No.26267M No.SALUD-2011-01-161930 the NIH,No.UL1TR000124 to Crespi CM,and NIH/NCI No.K07CA197179 to Flores YN 

主　　题：Liver disease Risk factors Health disparities Mexico Mexican Americans Latinos 

摘      要：AIM To compare the prevalence of chronic liver disease(CLD) risk factors in a representative sample of MexicanAmericans born in the United States(US) or Mexico, to a sample of adults in *** Data for Mexican-Americans in the US were obtained from the 1999-2014 National Health and Nutrition Examination Survey(NHANES), which includes persons of Mexican origin living in the US(n = 4274). The NHANES sample was restricted to Mexican-American participants who were 20 years and older, born in the US or Mexico, not pregnant or breastfeeding, and with medical *** data in Mexico were obtained from the 2004-2013 Health Worker Cohort Study in Cuernavaca, Mexico(n =9485). The following known risk factors for liver disease/cancer were evaluated: elevated aminotransferase levels(elevated alanine aminotransferase was defined as 40 IU/L for males and females; elevated aspartate aminotransferase was defined as 40 IU/L for males and females), infection with hepatitis B or hepatitis C,metabolic syndrome, high total cholesterol, diabetes,obesity, abdominal obesity, and heavy alcohol use. The main independent variables for this study classified individuals by country of residence(i.e., Mexico vs the US) and place of birth(i.e., US-born vs Mexico-born).Regression analyses were used to investigate CLD risk *** After adjusting for socio-demographic characteristics,Mexican-American males were more likely to be obese,diabetic, heavy/binge drinkers or have abdominal obesity than males in Mexico. The adjusted multivariate results for females also indicate that Mexican-American females were significantly more likely to be obese, diabetic, be heavy/binge drinkers or have abdominal obesity than Mexican females. The prevalence ratios and prevalence differences mirror the multivariate analysis findings for the aforementioned risk factors, showing a greater risk among US-born as compared to Mexico-born MexicanAmericans. CONCLUSION In this study, Mexican-Americans i