Concurrent infection with Ranavirus, <i>Batrachochytrium dendrobatidis</i>, and <i>Aeromonas</i> in a captive anuran colony

作     者：Miller, Debra L. Rajeev, Sreekumari Brookins, Milagros Cook, Jeff Whittington, Lisa Baldwin, Charles A. 

作者机构：Univ Georgia Coll Vet Med Vet Diagnost & Invest Lab Tifton GA 31793 USA Reptiland Allenwood PA 17810 USA 

出 版 物：《JOURNAL OF ZOO AND WILDLIFE MEDICINE》 (动物园和野生动物医学杂志)

年 卷 期：2008年第39卷第3期

页      面：445-449页

核心收录：

学科分类：0906[农学-兽医学] 09[农学] 

主　　题：Aeromonas hydrophila anuran Batrachochytrium dendrobatidis concurrent infection Ranavirus 

摘      要：Four species (Dendrobates auratus, Phyllobates terribilis, Pyxicephalus adspersus, and Rhacophorus dennysi) of captive anurans with a clinical history of lethargy and inappetence were found dead and were submitted for necropsy. Gross lesions included irregular patches of sloughed skin and rare dermal ulcerations. Histologic findings included epidermal proliferation that was most Pronounced on the digits and that included intracytoplasmic chytrid organisms. Bacteria were often associated with the epidermal lesions. Intracytoplasmic inclusion bodies were observed in hepatocytes. Real-time polymerase chain reaction yielded positive results for both Ranavirus and Batrachochytrium dendrobatidis (Bd). Bacterial culture of internal organs yielded Aeromonas hydrophila. This is the first report of concurrent infections in anurans by Ranavirus and Bd and A. hydrophila.