"Hyperdense artery sign" in early ischemic stroke: diagnostic value of model-based reconstruction approach in comparison with standard hybrid iterative reconstruction algorithm

作     者：Lombardi, Sophie Riva, Luca Patassini, Mirko Remida, Paolo Capraro, Cristina Canonico, Francesco Franzesi, Cammillo Talei Ippolito, Davide 

作者机构：San Gerardo Hosp Dept Diagnost Radiol Via Pergolesi 33 I-20900 Monza MB Italy Univ Milano Bicocca Sch Med Via Cadore 48 I-20900 Monza MB Italy 

出 版 物：《NEURORADIOLOGY》 (神经放射学)

年 卷 期：2018年第60卷第12期

页      面：1273-1280页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1006[医学-中西医结合] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 100106[医学-放射医学] 1009[医学-特种医学] 10[医学] 100602[医学-中西医结合临床] 

主　　题：Computed tomography Brain CT Hyperdense artery sign Brain stroke Iterative reconstruction algorithm 

摘      要：PurposeHyperdense artery sign is the earliest sign of ischemic stroke on non-enhanced computed tomography and it can be visible long before parenchymal changes. The aim of our study was to compare diagnostic value of model-based iterative reconstruction algorithm (IMR) with that of iterative reconstruction algorithm (iDose4) in identifying hyperdense artery *** selected 56 consecutive patients suspected for ischemic stroke, who underwent a NCCT and that demonstrated a vessel occlusion at angio-CT or developed ischemic lesion at follow-up CT. Two readers randomly analyzed images of NCCT reconstructed both with iDose4 (4mm) and IMR (2mm), reporting presence of hyperdense artery sign (0: no;1: yes;2: not sure). They rated image quality on a 4-point scale (1: unacceptable;4: more than average) and recorded HU values of clot and of normal vessel and measured noise index, CNR and *** values of CTDI, DLP, and ED were respectively of 43mGy, 819.7mGycm, and *** analyzing the IMR reconstruction, both readers were able to recognize hyperdense vessel sign in 55/56 patients, while only in 12/56 patients were identified with *** obtained better rating of image quality (mean score for IMR 3.32 vs 2.53 for iDose), higher clot density (57.2 vs 46.7 HU), lower noise index (5 vs 2), higher CNR and SNR (respectively 4.2 vs 2 and 16.8 vs 8.5).ConclusionsModel-based approach significantly increases sensitivity in detecting hyperdense artery sign, offering higher SNR and CNR in brain CT images in comparison with standard hybrid reconstruction algorithm.