Real-time detection of influenza A virus using semiconductor nanophotonics

作     者：Dominic Lepage Alvaro Jimenez Jacques Beauvais Jan J Dubowski 

作者机构：Laboratory for Quantum Semiconductors and Photon-based BioNanotechnologyInterdisciplinary Institute for Technological Innovation(3IT)Department of Electrical and Computer EngineeringUniversite´de SherbrookeSherbrookeQC J1K 2R1Canada 

出 版 物：《Light(Science & Applications)》 (光（科学与应用)（英文版）)

年 卷 期：2013年第2卷第1期

页      面：184-191页

核心收录：

学科分类：0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 

基　　金：The authors acknowledge the financial contribution from the Natural Science and Engineering Research Council of Canada(NSERC Strategic grant STPGP 350501-07) the Canada Research Chair in Quantum Semiconductors Program and the Vanier Scholarship CGS program 

主　　题：GaAs/AlGaAs quantum well device hyperspectral imaging technology influenza A virus integrated surface plasmon resonance biosensor 

摘      要：Modern miniaturization and the digitalization of characterization instruments greatly facilitate the diffusion of technological advances in new fields and generate innovative *** concept of a portable,inexpensive and semi-automated biosensing platform,or lab-on-a-chip,is a vision shared by many researchers and venture *** this scope,we present a semiconductor monolithic integration approach to conduct surface plasmon resonance *** technology is already commonly used for biochemical characterization in pharmaceutical industries,but we have reduced the technological platform to a few nanometers in scale on a semiconductor *** evaluate the signal quality of this nanophotonic device using hyperspectral-imaging technology,and we compare its performance with that of a standard prism-based commercial *** standard biochemical agents are employed for this characterization study:bovine serum albumin and inactivated influenza A *** resolutions of data acquisition varying between 360 and 2.2 s are presented,yielding 2.731025–1.531026 RIU resolutions,respectively.