High performance modelling of the transport of energetic particles for photon radiotherapy

作     者：Birindelli, Gabriele Feugeas, Jean-Luc Caron, Jerome Dubroca, Bruno Kantor, Guy Page, Jonathan Pichard, Teddy Tikhonchuk, Vladimir Nicolai, Philippe 

作者机构：Univ Bordeaux CNRS CEA CELIACtr Laser Intenses & Applicat F-33400 Talence France Inst Bergonie Comprehens Canc Ctr Dept Radiotherapy F-33076 Bordeaux France 

出 版 物：《PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS》 (医学物理)

年 卷 期：2017年第42卷

页      面：305-312页

核心收录：

学科分类：1009[医学-特种医学] 10[医学] 

基　　金：Aquitaine Regional Council [N11002122-012] FEDER [N Progos 11002059/N Presage: 36050] 

主　　题：Radiotherapy treatment planning system Deterministic dose calculation Monte-Carlo algorithm Boltzmann equation 

摘      要：This work consists of the validation of a new Grid Based Boltzmann Solver (GBBS) conceived for the description of the transport and energy deposition by energetic particles for radiotherapy purposes. The entropic closure and a compact mathematical formulation allow our code (M1) to calculate the delivered dose with an accuracy comparable to the Monte-Carlo (MC) codes with a computational time that is reduced to the order of few minutes without any special processing power requirement. A validation protocol with heterogeneity inserts has been defined for different photon sources. The comparison with the MC calculated depth-dose curves and transverse profiles of the beam at different depths shows an excellent accuracy of the M1 model. (C) 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.