Skin Layer at the Actin-Gel Surface: Quenched Protein Membranes form Flat, Crumpled, and Tubular Morphologies

作     者：L. S. Hirst C. R. Safinya 

作者机构：Materials & Physics Departments Biomolecular Science and Engineering Program University of California 

出 版 物：《Physical Review Letters》 (Phys. Rev. Lett.)

年 卷 期：2004年第93卷第1期

页      面：018101-018101页

核心收录：

学科分类：07[理学] 0702[理学-物理学] 

基　　金：National Institute of General Medical Sciences  NIGMS  (R01GM059288) 

主　　题：.actinin actin laments isotropic gel Skin Layer Protein Membranes network of bundles 

摘      要：We report the discovery of a hierarchically structured skin layer formed at the surface of an isotropic gel of filamentous actin bundles at high molar ratios of α-actinin, an actin cross-linker, to globular actin. Confocal microscopy has elucidated the full, micron scale 3D structure. The protein skin layer, composed of a directed network of bundles, exhibits flat, crumpled, tubelike and pleated multitubular morphologies, resulting from stresses due to the underlying gel. The skin layer, which readily detaches, constitutes a model anisotropic solid membrane with stress-induced, quenched disorder.