Topical therapy for acne vulgaris - How do you choose the best drug for each patient?

作     者：Johnson, BA Nunley, JR 

作者机构：Virginia Commonwealth Univ Univ Student Hlth Serv Richmond VA 23298 USA 

出 版 物：《POSTGRADUATE MEDICINE》 (Postgrad. Med.)

年 卷 期：2000年第107卷第3期

页      面：69-+页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学] 

主　　题：痤疮 寻常/分类 痤疮 寻常/诊断 痤疮 寻常/药物疗法 投药 局部 抗菌药/投药和剂量 抗菌药/治疗应用 皮肤科用药/投药和剂量 诊断 鉴别 复方合剂 药物疗法 联合 角质溶解药/投药和剂量 维甲酸/投药和剂量 人类 

摘      要：Although management of acne is sometimes difficult, primary care physicians can offer a number of treatment plans to patients with this skin condition. Comedonal acne usually responds to topical keratolytics, such as salicylic acid, benzoyl peroxide, adapalene, and tretinoin. Inflammatory acne is usually treated with topical therapy plus a systemic antibiotic. Nodulocystic acne generally requires an 8-week course of systemic antibiotics. If the nodulocystic acne does not improve, minocycline or isotretinoin may be needed. Topical therapy is often helpful in the long-term management of nodulocystic acne. New products are available that deliver topical agents in novel ways that decrease skin irritation. With the proper tools and instructions in use, most patients have significant improvement in their acne.