Synthesis and Properties of Micron-size Magnetic Polymer Spheres with Epoxy Groups

作     者：刘先桥 官月平 邢建民 马志亚 刘会洲 LIU Xianqiao;GUAN Yueping;XING Jianmin;MA Zhiya;LIU Huizhou

作者机构：Laboratory of Separation Science and EngineeringState Key Laboratory of Biochemical EngineeringInstitute of Process EngineeringChinese Academy of SciencesBeijing 100080China 

出 版 物：《Chinese Journal of Chemical Engineering》 (中国化学工程学报（英文版）)

年 卷 期：2003年第11卷第6期

页      面：731-735页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070305[理学-高分子化学与物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 

基　　金：Supported by the High-Technology Research and Development Program of China(No.2002AA302211)and the National Natural science Foundation of China(No.20206032) 

主　　题：magnetic microsphere synthesis suspension polymerization bioseparation 

摘      要：Micron-size superparamagnetic poly(styrene-divinylbenzene-glycidyl methacrylate) (PSt-DVB-GMA) spheres were prepared via a modified suspension copolymerization method. Oleic acid coated magnetite (Fe3O4 nanoparticles made by co-precipitation were first mixed with monomers of St, DVB, GMA, and benzoyl peroxide (BPO) to form oil in water suspension with the presence of poly(viny) pyrrolidone) (PVP-K30) as a stabilizer. Then the temperature of mixture was increased at a controlled rate to obtain small and relatively uniform droplets. Finally, the copolymerization reaction was initiated by the decomposition of BPO. The morphology and properties of magnetic PSt-DVB-GMA microspheres were examined by SEM, TEM, VSM, XRD and FT-IR. The magnetic microspheres obtained have very small size (about 4-7μm) in diameter with narrow size distribution and super-paramagnetic characteristics. Powder X-ray diffraction measurements show the inverse cubic spinel structure for the magnetite dispersed in polymer microspheres. FT-IR spectroscopy indicates extensive oxirane groups existed on the surface of magnetic PSt-DVB-GMA microspheres.