Clinical research - Flawed cancer study leads to shake-up at Univ. of Oklahoma

作     者：Malakoff, D 

出 版 物：《SCIENCE》 (Science)

年 卷 期：2000年第289卷第5480期

页      面：706-707页

核心收录：

学科分类：07[理学] 08[工学] 

主　　题：癌症疫苗/治疗应用 临床方案/标准 临床试验(主题)/标准 人类实验 黑色素瘤/药物疗法 俄克拉何马 专家委员会 美国 美国卫生和人类服务部 大学 人类 

摘      要：Allegations of lax safety procedures and flawed management in a clinical cancer trial have cost four researchers and administrators their jobs at the University of Oklahoma. They have also led to a temporary shutdown of 75 clinical trials at the university s Health Science Center in Tulsa and a sweeping overhaul of the school s process for approving human experiments. University officials emphasize that none of the roughly 100 patients involved in the 3-year-old study of an experimental cancer vaccine was known to have been harmed, and that most trials will soon be restarted.