Oncofertility in adolescent and young adult hereditary cancer: Considerations for genetics professionals

作     者：Gwendolyn P Quinn Beth N Peshkin Ivana Sehovic Meghan Bowman Christina Tamargo Susan T Vadaparampil 

作者机构：Health Out-comes and Behavior ProgramMoffitt Cancer CenterDepartment of Oncologic SciencesMorsani College of MedicineUniversity of South Florida Cancer Prevention and Control ProgramGeorgetown Lombardi Comprehensive Cancer Center Health Outcomes and Behavior ProgramMoffitt Cancer Center 

出 版 物：《World Journal of Medical Genetics》 (世界医学遗传学杂志)

年 卷 期：2015年第5卷第4期

页      面：52-59页

学科分类：12[管理学] 1204[管理学-公共管理] 120402[管理学-社会医学与卫生事业管理(可授管理学、医学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 10[医学] 

主　　题：Fertility Oncology Genetic counselors Decision-making Oncofertility Adolescent young adults Training Health professionals 

摘      要：Adolescents and young adults(AYA)with a cancer diagnosis or those at risk for cancer due to hereditary cancer syndromes may benefit from genetic counseling and testing not only to manage personal risk but also to address reproductive concerns,especially *** opportunity for genetic counselors to provide important risk information is relevant to both the newly diagnosed as well as to unaffected carriers and ***,genetic counselors may need additional training in reproductive options related to AYA cancer to provide this valuable *** commentary uses hereditary breast and ovarian cancer syndrome as a model to highlight important considerations when discussing preimplanatation genetic diagnosis and prenatal diagnosis,particularly in the context of expanded testing for hereditary cancer risk including multigene panels or whole exome or whole genome *** hereditary cancers are also addressed;however,less is known about the psychosocial and fertility concerns in these AYA ***,we provide an overview of the concept ofoncofertility-the linkage between cancer care and reproductive medicine that aims to expand the reproductive opportunities of cancer patients-and offer support for the expansion of guidelines to include genetic counselors in AYA cancer patients’treatment planning related to reproductive health and fertility.