Bipolar cell pathways for color vision in non-primate dichromats

作     者：Puller, Christian Haverkamp, Silke 

作者机构：Max Planck Inst Brain Res Dept Neuroanat D-60528 Frankfurt Germany 

出 版 物：《VISUAL NEUROSCIENCE》 (视神经学)

年 卷 期：2011年第28卷第1期

页      面：51-60页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 10[医学] 

基　　金：DFG [HA 5277/2-2] 

主　　题：Color coding Parallel pathways Blue cone bipolar cells Horizontal cells Glutamate receptors 

摘      要：Color vision in mammals is based on the expression of at least two cone opsins that are sensitive to different wavelengths of light. Furthermore, retinal pathways conveying color-opponent signals are required for color discrimination. Most of the primates are trichromats, and color-coded channels of their retinas are unveiled to a large extent. In contrast, knowledge of cone-selective pathways in nonprimate dichromats is only slowly emerging, although retinas of dichromats like mice or rats are extensively studied as model systems for retinal information processing. Here, we review recent progress of research on color-coded pathways in nonprimate dichromats to identify differences or similarities between di- and trichromatic mammals. In addition, we applied immunohistochemical methods and confocal microscopy to retinas of different species and present data on their neuronal properties, which are expected to contribute to color vision. Basic neuronal features such as the blue cone bipolar cell exist in every species investigated so far. Moreover, there is increasing evidence for chromatic OFF channels in dichromats and retinal ganglion cells that relay color-opponent signals to the brain. In conclusion, di- and trichromats share similar retinal pathways for color transmission and processing.