Testicular Microlithiasis: Patient Compliance in a Two-Year Follow-Up Program

作     者：Pedersen, M. R. Osther, P. J. S. Soerensen, F. B. Rafaelsen, S. R. 

作者机构：Vejle Hosp Part Sygehus Lillebaelt Radiol Kabbeltoft 25 DK-7100 Vejle Denmark Fredercia Hosp Part Sygehus Lillebaelt Urol Res Ctr Fredericia Denmark Sygehus Lillebalt Vejle Sygehus Clin Pathol Vejle Denmark DCCG South Vejle Hosp Dept Radiol Vejle Denmark 

出 版 物：《ULTRASOUND INTERNATIONAL OPEN》 (Ultrasound Int. Open)

年 卷 期：2016年第2卷第4期

页      面：E113-E116页

主　　题：testicular microlithiasis testis cancer prevalence follow-up 

摘      要：Introduction: We present a retrospective 2-year follow-up cohort of 103 men with testicular microlithiasis (TML) and discuss patient compliance and the value of surveillance. Methods: A retrospective analysis of patients examined with scrotal ultrasonography (US) in the period from 2008 through 2010 was performed. A total of 103 men with TML were diagnosed and offered US follow-up every 6 months for 2 years. They were retrospectively analyzed regarding demographics and follow-up details, including the development of any kind of malignancy until March 2015, using the Danish Electronic Pathology Registry. Results: The prevalence of TML was 10.3 %. Of the 103 men with TML, 23 (22.3 %) had TML in the left testicle, 38 (36.9 %) in the right (p = 0.002), and 42 (40.8 %) had bilateral TML. Patient compliance was low with 11.7 % participating in all US follow-up examinations. 5 men presented risk factors (testicular atrophy (N = 1) and previous testicular cancer (N = 4)), but no cases of testicular malignancy were found in the follow-up period. Conclusion: The low patient compliance conflicts with the ESUR Scrotal Imaging Subcommittee guidelines that recommend scrotal US follow-up annually for TML until the age of 55 years. The fact that no cancers were found during follow-up using the pathology registry calls the value of follow-up into question.