Hematopoietic stem-cell transplantation from an unrelated donor

作     者：McGlave, P Cassileth, PA 

作者机构：Univ Minnesota Sch Med Div Hematol Oncol & Transplantat Minneapolis MN 55455 USA 

出 版 物：《HOSPITAL PRACTICE》 (Hosp. Pract.)

年 卷 期：2000年第35卷第8期

页      面：43-+页

核心收录：

学科分类：12[管理学] 1204[管理学-公共管理] 120402[管理学-社会医学与卫生事业管理(可授管理学、医学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 10[医学] 

基　　金：NCI NIH HHS [P01CA65493  P30CA77598] Funding Source: Medline 

主　　题：算法 骨髓检查 决策树 造血干细胞移植/方法 造血干细胞移植/发展趋势 组织相容性试验 干扰素α/治疗应用 白血病 髓系 慢性 BCR-ABL阳性/血液 白血病 髓系 慢性 BCR-ABL阳性/诊断 白血病 髓系 慢性 BCR-ABL阳性/治疗 白细胞计数 病人教育(主题) 病人遴选 费城染色体 移植 同种/方法 移植 同种/发展趋势 治疗结果 成年人 人类 男(雄)性 

摘      要：When an HLA-matched sibling is not available and nontransplant approaches have been ineffective, transplantation of hematopoietic stem cells from an unrelated donor can effect a cure in some patients with chronic myelogenous leukemia Even when successful, however, transplantation is a rigorous and prolonged process whose complications include infection and graft-versus-host disease. Improvements in hematopoietic stem-cell transplantation as well as innovative nontransplant approaches may improve the outcome in these patients.