Numerical approaches for dipole modeling in finite element method based source analysis

作     者：Wolters, C.H. Köstler, H. Möller, C. Härdtlein, J. Anwander, A. 

作者机构：Institute for Biomagnetism and Biosignalanalysis Münster University Hospital Münster Germany Scientific Computing and Imaging Institute University of Utah Salt Lake City United States Department of Computer Science 10 University Erlangen-Nuremberg Erlangen Germany Max Planck Institute for Human Cognitive and Brain Sciences Leipzig Germany 

出 版 物：《International Congress Series》 (Int. Congr. Ser.)

年 卷 期：2007年第1300卷

页      面：189-192页

学科分类：1002[医学-临床医学] 07[理学] 08[工学] 

基　　金：Deutsche Forschungsgemeinschaft  DFG  (WO 1425/1-1) 

主　　题：Dipole Direct potential approach EEG Finite Element method MEG Singularity treatment Source analysis Subtraction method 

摘      要：In EEG/MEG source analysis, a mathematical dipole is widely used as the atomic structure of the primary current distribution. When using realistic finite element models for the forward problem, the current dipole introduces a singularity on the right-hand side of the governing differential equation that has to be treated specifically. We evaluated and compared three different numerical approaches, a subtraction method, a direct approach using partial integration and a direct approach using the principle of Saint Venant. Evaluation and comparison were carried out in a four-layer sphere model using quasi-analytical formulas. © 2007 Elsevier B.V. All rights reserved.