叶酸卟啉化合物的合成

作     者：刁俊林 李东红 

作者机构：创伤烧伤复合伤国家重点实验室第三军医大学大坪医院野战外科研究所二室重庆400042 

出 版 物：《化学研究与应用》 (Chemical Research and Application)

年 卷 期：2009年第21卷第11期

页      面：1575-1577页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

主　　题：卟啉 叶酸 靶向光敏剂 合成 

摘      要：In order to obtain a molecular-targeting photosensitizer mediated by folate receptor,5-p-(4-aminobutoxyphenyl)-10,15,20-tri-p-methoxyphenylporphyrin was synthesized with a four-step procedure starting from p-hydroxybenzaldehyde,p-methoxybenzaldehyde and pyrrole,then,a novel folate-porphyrin compound was prepared through a condensation reaction of the aminoporphyrin with actived folic *** structure was characterized by IR,UV-Vis,MS and 1HNMR spectra.