Duplication of the pituitary gland in a newborn with median cleft face syndrome and nasal

作     者：Hamon-Kerautret, M Ares, GS Demondion, X Rouland, V Francke, JP Pruvo, JP 

作者机构：CHRU Lille Hop Roger Salengro Serv Neuroradiol Lille France CHRU Lille Hop Roger Salengro Serv Neonatol Lille France Univ Lille Fac Med Dept Anat Villeneuve Dascq France 

出 版 物：《PEDIATRIC RADIOLOGY》 (儿科放射学)

年 卷 期：1998年第28卷第5期

页      面：290-292页

核心收录：

学科分类：1002[医学-临床医学] 100202[医学-儿科学] 1009[医学-特种医学] 10[医学] 

摘      要：A newborn suffered immediate neonatal respiratory distress because of an obstructive, soft-tissue nasal mass. Clinical examination revealed a cleft palate with a protruding polypoid mass. CT and MRI showed a heterogeneous nasopharyngeal mass and associated intracranial abnormalities-duplication of the hypophysis and hypoplasia of the corpus callosum. Duplication of the hypophysis is a very rare malformation, only 13 cases having been previously described. The suggested pathogenesis is duplication of the prechordal plate and anterior end of the notochord during early embryological development.