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作者机构:MOE Key Laboratory of Material Physics and Chemistry under Extraordinary Conditions Shanxi Key Laboratory of Macromolecular Science and Technology School of Science Northwestern Polytechnical University Xi'an China Hefei National Laboratory for Physical Sciences at the Microscale CAS Key Laboratory of Soft Matter Chemistry Anhui Key Laboratory of Optoelectronic Science and Technology Department of Polymer Science and Engineering University of Science and Technology of China Hefei China Max Planck Institute for Polymer Research Ackermannweg 10 Mainz Germany
出 版 物:《ADVANCED THERAPEUTICS》 (Adv. Ther.)
年 卷 期:2019年第2卷第5期
核心收录:
基 金:Fonds der ChemischenIndustrie, (661548) Max Planck Graduate Center mit der Johannes Gutenberg-Universität Mainz Deutsche Forschungsgemeinschaft, DFG, (WU 787/10-1, WU 787/2-1, WU 787/8-1) National Natural Science Foundation of China, NSFC, (21674086) Natural Science Foundation of Shaanxi Province, (2018JZ2003) Recruitment Program of Global Experts
主 题:drug delivery nanomedicine polymers supramolecules therapeutics
摘 要:An elegant combination of supramolecular polymers exhibiting nonlinear topological structures results in a series of brand new, nonlinear supramolecular polymers. Recently, these polymers have attracted increased attention in various fields due to their diverse and advantageous properties. Especially in therapeutic applications, one can take advantage of their unique chemical, physical, and biological properties such as degradability and stimuli-responsiveness. Due to the large number of possible module modifications, such polymers have great potential as platforms in disease treatments. In this review, the structures, properties, and functions of different nonlinear supramolecular polymers are summarized. Current therapeutic applications are presented and the prospective design trends are discussed for promoting the development of nonlinear supramolecular polymers.