PARTIAL UNCOUPLING, OR INHIBITION OF ELECTRON-TRANSPORT RATE, HAVE EQUIVALENT EFFECTS ON THE RELATIONSHIP BETWEEN THE RATE OF ATP SYNTHESIS AND PROTON-MOTIVE FORCE IN SUBMITOCHONDRIAL PARTICLES

作     者：SORGATO, MC LIPPE, G SEREN, S FERGUSON, SJ 

作者机构：CNRSTUDY MITOCHONDRIAL PHYSIOL UNITI-35131 PADOVAITALY UNIV BIRMINGHAMDEPT BIOCHEMBIRMINGHAM B15 2TTW MIDLANDSENGLAND 

出 版 物：《FEBS LETTERS》 (欧洲生化学会联合会快报)

年 卷 期：1985年第181卷第2期

页      面：323-327页

核心收录：

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 07[理学] 

基　　金：North Atlantic Treaty Organization  NATO  (1771) 

主　　题：ATP-synthesis rate Submitochondrial particle Proton-motive force Localised proton coupling Energy transduction Δp, proton-motive force Δμ̃ H / F = Δψ + RT 2.303/ F ·ΔpH Δψ is the electrical component and ΔpH the chemical component of the electrochemical gradient of protons (Δμ H ) existing across an energy-transducing membrane F , the Faraday constant Ap 5 A, P 1 ,P 5 -di(adenosine-5'-)pentaphosphate FCCP, carbonyl cyanide p -trifluoromethoxyphenylhydrazone CCCP, carbonyl cyanide m -chlorophenylhydrazone SMP, submitochondrial particles 

摘      要：The rates of electron transport and of ATP synthesis have been measured in bovine heart Mg-ATP submitochondrial particles oxidising succinate under conditions of partial attenuation of the proton-motive force by malonate or FCCP. This paper reports evidence that the relationship between the rate of ATP synthesis and the magnitude of the proton motive force is independent of the mode by which the decrease of the proton motive force is achieved.