REGULATION OF ARGININE METABOLISM IN SACCHAROMYCES-CEREVISIAE - EXPRESSION OF THE 3 ARGR REGULATORY GENES AND CELLULAR-LOCALIZATION OF THEIR PRODUCTS

作     者：BERCY, J DUBOIS, E MESSENGUY, F 

作者机构：CTR ENSEIGNMENT & RECH IND ALIMENTAIRES INST RECH 1 AVE EMILE GRYSON B-1070 BRUSSELS BELGIUM UNIV LIBRE BRUXELLES FAC SCI MICROBIOL LAB B-1070 BRUSSELS BELGIUM 

出 版 物：《GENE》 (基因)

年 卷 期：1987年第55卷第2-3期

页      面：277-285页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 09[农学] 

主　　题：coding sequence lacZ fusion Recombinant DNA regulatory proteins subcellular localization yeast 

摘      要：Three regulatory proteins are involved in the control arginine metabolism in yeast: ARGRI, ARGRII and ARGRIII. The control region and part of the coding sequence of the ARGR genes were fused to the Escherichia coli lacZ gene. These chimeras were used to study the expression of the regulatory genes as well as the cellular compartmentalization of the regulatory products. Our results show that the three ARGR proteins are localized in the nucleus and that their synthesis is not regulated by arginine nor by any of the other ARGR products. However, some data suggest that the ARGRIII protein could control ARGRI activity.