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Carotenoid biosynthesis in extremophilic Deinococcus-Thermus bacteria

在 extremophilic DeinococcusThermus 细菌的类胡萝卜素生合成

作     者:Tian, Bing Hua, Yuejin 

作者机构:Zhejiang Univ Key Lab Nucl Agr Sci Chinese Minist Agr & Zhejiang Prov Inst Nucl Agr Sci Hangzhou 310029 Zhejiang Peoples R China 

出 版 物:《TRENDS IN MICROBIOLOGY》 (微生物学趋势)

年 卷 期:2010年第18卷第11期

页      面:512-520页

核心收录:

学科分类:0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 07[理学] 071005[理学-微生物学] 10[医学] 

基  金:National Basic Research Program of China [2007CB707804] National Hi-Tech Development Program [2007AA021305] National Natural Science Foundation of China [30830006, 30670026, 30870035] Chinese Ministry of Agriculture 

主  题:CAROTENOIDS BIOSYNTHESIS DEINOCOCCUS OXIDATIVE stress MICROBIOLOGY of extreme environments BIOLOGICAL pigments CELLULAR signal transduction RADIATION 

摘      要:Bacteria from the phylum Deinococcus-Thermus are known for their resistance to extreme stresses including radiation, oxidation, desiccation and high temperature. Cultured Deinococcus-Thermus bacteria are usually red or yellow pigmented because of their ability to synthesize carotenoids. Unique carotenoids found in these bacteria include deinoxanthin from Deinococcus radio-durans and thermozeaxanthins from Thermus thermophilus. Investigations of carotenogenesis will help to understand cellular stress resistance of Deinococcus-Thermus bacteria. Here, we discuss the recent progress toward identifying carotenoids, carotenoid biosynthetic enzymes and pathways in some species of Deinococcus-Thermus extremophiles. In addition, we also discuss the roles of carotenoids in these extreme bacteria.

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