RESPIRATORY SINUS ARRHYTHMIA IN MAN - RELATION TO CARDIOVASCULAR PRESSURES

作     者：FREYSCHUSS, U MELCHER, A 

作者机构：KAROLINSKA SJUKHUSET DEPT CLIN PHYSIOL S-10401 STOCKHOLM 60 SWEDEN 

出 版 物：《SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION》 (斯堪的纳维亚临床与实验研究杂志)

年 卷 期：1976年第36卷第3期

页      面：221-229页

核心收录：

学科分类：1001[医学-基础医学(可授医学、理学学位)] 1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

基　　金：Forenade Liv insurance company Karolinska Institutet, KI 

主　　题：Baroreceptor reflexes heart rate regulation intermittent positive-pressure ventilation venous return 

摘      要：The relationship of respiratory sinus arrhythmia (RSA) to the accompanying oscillations of cardiovascular pressures was studied in 5 healthy subjects. Tidal volumes (VT) of 1.0, 1.5, 2.0 l at a breathing rate of 6 c/min were used as reference. With identical VT, esophageal pressure was varied by negative inspiratory pressure (NIP) and intermittent positive-pressure ventilation (IPPV). Compared with control, NIP with 1.01 significantly increased RSA, the oscillations of brachial artery pressures (PBA), and the net filling pressures of the ventricles. IPPV did not significantly change the variations of PBA but reduced RSA and the respiratory variations of the right ventricular end-diastolic net pressure. During control breathing and with NIP the acceleration of heart rate during inspiration was associated with rising PBA and rising net filling pressures of both ventricles. RSA may be elicited by cardiovascular reflexes due to changes in venous filling of the heart rather than by the variations in systemic arterial pressure.