The Origin and Significance of Randall's Plaque in Nephrolithiasis

作     者：Miller, Nicole L. 

作者机构：Vanderbilt Univ Sch Med Dept Urol Surg Nashville TN 37212 USA 

出 版 物：《JOURNAL OF UROLOGY》 (泌尿学杂志)

年 卷 期：2011年第186卷第3期

页      面：783-784页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Nephrolithiasis Kidney Essences International Data Encryption Algorithm new technology Crystallization Alexander 

摘      要：H. Gr. Wells said, \Human history is in essence a history of ideas.\ I would propose that there are some ideas that must wait to be realized, whether for some new technology or simply the willingness to challenge the current understanding, and I believe this is the case for Randall\ s plaque (RP). The RP theory of stone pathogenesis is not new. As early as 1937 Alexander Randall, using a series of cadaveric kidneys, described interstitial papillary and medullary deposits of apatite (plaque) in approximately 20% of kidneys and in some cases stones attached to this plaque.1 Randall hypothesized this plaque was the perfect nidus for crystallization.