Dopamine hydrochloride and carboxymethyl chitosan coatings for multifilament surgical suture and their influence on friction during sliding contact with skin substitute

作     者：Gangqiang ZHANG Ganlin ZHENG Tianhui REN Xiangqiong ZENG Emile van der HEIDE Gangqiang ZHANG;Ganlin ZHENG;Tianhui REN;Xiangqiong ZENG;Emile van der HEIDE

作者机构：Advanced Lubricating Materials LaboratoryShanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201210China Institute of Functional Textiles and Advanced MaterialsColloge of Textlies&ClothingQingdao UniversityQingdao 266000China School of Chemistry and Chemical EngineeringKey Laboratory of Thin Film and Microfabrication Technology(Ministry of Education)Shanghai Jiao Tong UniversityShanghai 200240China Laboratory for Surface Technology and TribologyUniversity of TwenteEnschede 7500AEThe Netherlands TU DelftFaculty of Civil Engineering and GeosciencesStevinweg 1Delft 2628 CNThe Netherlands Soete LaboratoryGhent UniversityZwijnaarde B-9052Belgiu 

出 版 物：《Friction》 (摩擦（英文版）)

年 卷 期：2020年第8卷第1期

页      面：58-69页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：Marie Curie CIG(Grant no.PCIG10-GA-2011-303922) the Shanghai Natural Science Foundation(Grant no.17ZR1442100) the Shanghai Municipal “Science and Technology Innovation Action Plan” International Cooperation Project(no.15540723600)for the financial support 

主　　题：friction surgical suture coating Biomaterials skin substitute 

摘      要：In order to reduce the damage to tissue and fill the interstices between fibers,multifilament sutures are frequently treated with certain coating *** objective of this study was to create and characterize dopamine hydrochloride(DA)and carboxymethyl chitosan(CMCS)coatings on surgical sutures and investigate their effects on the frictional performance of the surgical sutures during sliding through a skin *** effects of the treatment on the physical and chemical characteristics of the surgical sutures were *** friction force of the surgical sutures during sliding through the skin substitute was experimentally determined using a penetration friction *** coefficient of friction(COF)was calculated using a linear elastic model and was used to estimate the frictional behavior of the surgical suture‐skin *** results showed that the DA coating could evenly deposit on the surface of the etched multifilament surgical suture surfaces in a weakly alkaline buffer *** CMCS coating material could form a uniform film on the surface of the *** changes in the surface roughness of the multifilament surgical sutures with different treatments occurred in this *** friction force and the COF of the multifilament surgical sutures with DA and CMCS coating showed little change when compared with untreated multifilament surgical sutures.