Does preservative-free lignocaine 1% for hydrodissection reduce pain during phacoemulsification?

作     者：Tan, JHY Burton, RL 

作者机构：W Norwich Hosp Dept Ophthalmol Norwich Norfolk England 

出 版 物：《JOURNAL OF CATARACT AND REFRACTIVE SURGERY》 (白内障与屈光外科学杂志)

年 卷 期：2000年第26卷第5期

页      面：733-735页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：麻醉 局部/方法 麻醉药 局部/投药和剂量 麻醉药 局部/治疗应用 双盲法 等渗溶液/投药和剂量 等渗溶液/治疗应用 利多卡因/投药和剂量 利多卡因/治疗应用 眼药水/投药和剂量 眼药水/治疗应用 疼痛/药物疗法 疼痛测定 姑息疗法 超声乳化白内障吸除术 防腐剂 药物 前瞻性研究 人类 

摘      要：Purpose: To compare preservative-free 1% lignocaine with balanced salt solution (BSS(R)) in alleviating pain during hydrodissection in phacoemulsification cataract surgery. Setting: West Norwich Hospital, Norfolk, United Kingdom. Methods: This prospective double-masked trial comprised 68 patients having a day-case phacoemulsification cataract surgery. Patients were randomly divided into 2 groups, receiving either BSS or lignocaine 1% solution for hydrodissection during routine uneventful phacoemulsification using topical anesthesia. The level of intraoperative pain was scored on a scale of 0 (no pain) to 10 (severe pain), and the scores between the 2 groups were compared. Results: Of the 68 patients, 33 (49%) received BSS and 35 (51%), lignocaine 1% solution. A pain score greater than 2 was considered clinically significant;28 patients (85%) in the BSS group and 25 (71%) in the lignocaine 1% group scored 2 or less. The chi-square and Mann-Whitney tests found no significant difference between the BSS and lignocaine 1% groups (P = .30 and P = .432, respectively). Conclusion: There was no significant difference in the pain scores in patients who received BSS or lignocaine 1% solution. Thus, we conclude that hydrodissecting with lignocaine 1% solution does not provide added pain relief during phacoemulsification. J Cataract Refract Surg 2000;26:733-735 (C) 2000 ASCRS and ESCRS.