Poly (L-leucine) modified carbon paste electrode as an electrochemical sensor for the detection of paracetamol in presence of folic acid

作     者：Naik, T.S. Sunil Kumar Swamy, B.E. Kumara Ramamurthy, Praveen C. Chetankumar, K. 

作者机构：Department of P. G. Studies and Research in Industrial Chemistry Kuvempu University Jnana Sahyadri Shankaraghatta -577451 ShivamogaKarnataka India Department of Materials Engineering Indian Institute of Science Bangalore India 

出 版 物：《Materials Science for Energy Technologies》 (Mater. Sci. Energy. Technol.)

年 卷 期：2020年第3卷

页      面：626-632页

核心收录：

基　　金：The authors gratefully acknowledge the financial support from Dr. D. S. Kothari Post-Doctoral Fellowship Scheme  University Grants Commission   New Delhi  India 

主　　题：Electrochemical sensors 

摘      要：Here, L-leucine based electrochemical sensor was designed for the simultaneous analysis of paracetamol (PA) and folic acid (FA). Electropolymerization of L-leucine was carried out on the surface of the carbon paste electrode (CPE). The electrochemical deeds of the biomolecules were explored through cyclic voltammetry (CV) and differential pulse voltammetry (DPV) at the fabricated sensor. The invented poly (L-leucine) modified carbon paste electrode (PLCN-MCPE) showed very good interaction with the analyte molecules which results in the significant determination of PA and FA in terms of sensitivity and selectivity. The electrochemical reaction mechanism between the surface of the developed sensor and the analytes was carried out in terms of effects of scan rate, concentration, and the electrode process was found to be adsorption-controlled. The kinetics such as the number of electron transfer (n) and the heterogeneous rate constant (ko) were defined for PA and FA at MCPE. The lower limit of detection for PA and FA were assessed to be 0.44 and 2.4 µM correspondingly. As well, the availability of the sensor in real-world sample analysis was also investigated with satisfactory results. © 2020