Are there any subclinical myocardial dysfunctions in subjects with aortic valve sclerosis? A 3D-speckle tracking echocardiography study

作     者：Dogdus, Mustafa Yildirim, Arafat Kucukosmanoglu, Mehmet Kilic, Salih Yavuzgil, Oguz Nalbantgil, Sanem 

作者机构：Usak Univ Training & Res Hosp Dept Cardiol TR-64100 Usak Turkey Univ Hlth Sci Adana Training & Res Hosp Dept Cardiol TR-01060 Adana Turkey Ege Univ Dept Cardiol Fac Med TR-35100 Izmir Turkey 

出 版 物：《INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING》 (国际心脏血管成像杂志)

年 卷 期：2021年第37卷第1期

页      面：207-213页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 1009[医学-特种医学] 10[医学] 

主　　题：Aortic valve sclerosis 3D-speckle tracking echocardiography Subclinical left ventricular dysfunction 

摘      要：Aortic valve sclerosis (AVS) is defined as calcified and thickened aortic leaflets without restriction of leaflet motion. We have not found any studies that previously assessed the effect of AVS on myocardial functions with three dimensional-speckle tracking echocardiography (3D-STE). Therefore, we aimed to identify any early changes in left atrial (LA) myocardial dynamics and/or left ventricular (LV) systolic functions in patients with AVS using 3D-STE. Seventy-five patients with AVS and 80 age- and gender-matched controls were enrolled into the study. The baseline clinical characteristics of the study patients were recorded. Conventional 2D echocardiographic and 3D-STE analyses were performed. The LV-global longitudinal strain (LV-GLS) and LV-global circumferential strain (LV-GCS) were significantly decreased in the AVS (+) group than in the control group (p - 18 has 85.8% sensitivity, 67.5% specificity for the prediction of the AVS. Our results support that subjects with AVS may have subclinical LV deformation abnormalities even though they have not LV pressure overload. According to our findings, patients with AVS should be investigated in terms of atherosclerotic risk factors, their dysmetabolic status should be evaluated and closely followed up for their progression to calcific aortic stenosis.