Ulcerative colitis (UC), non-specific autoimmune disease, is a idiopathic, chronic, relapsing inflammatory conditions that are immunologically mediated and is characterized by bloody diarrhea, abdominal cramps, fatigu...
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Ulcerative colitis (UC), non-specific autoimmune disease, is a idiopathic, chronic, relapsing inflammatory conditions that are immunologically mediated and is characterized by bloody diarrhea, abdominal cramps, fatigue, weight loss, nausea, and so *** pathogenesis is inflammatory mucus of colon and *** of clinical studies indicate that the incidence of UC is 50-100 per 100 000, and the patients often develop UC at the age of 15-30 years ***, the risk of UC for people increases with change of diet structure, lifestyle and increasing pressure in modern *** with UC are at an increased risk of developing colorectal cancer, and so far, there isn't still an effective measure in ***, UC is regarded as one of refractory diseases by *** the etiologies of UC remains an enigma, the research work in animal models, human genetics and clinical trials, have provided new insights into the pathogenesis of these *** is evidence that it involves the interaction of the immune system, genetic susceptibility and the *** prevailing therapies for UC include glucocorticosteroids, sulfasalazine, and so ***, the therapies not only show limited benefits, but also have unwanted side ***, there is a need for alternative anti-inflammatory agents that are equally or more effective and cause fewer side *** constituents of plants, particularly Sophora alopecurodes L., have been reported to be useful in the management of inflammatory bowel diseases in Chinese fork medicine for a long *** are a mixture of extract from root or seed of Sophora alopecuroides L, Chinese medicine *** are mainly made up of six active components ***, sophocarpine, matrine, oxymatrine,sophoraramine, aloperine, and have been widely used as an ingredient approved by Chinese SFDA for many years, which contain not less than 24% sophoridine and not less than 95% alkaloids, calculated ref
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