Background.β-catenin is a transcriptional coactivator,itis critical to identify the target genes that in turn are responsible for the widespread roles of the pathway in many cellular and tissue *** it has critical ro...
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Background.β-catenin is a transcriptional coactivator,itis critical to identify the target genes that in turn are responsible for the widespread roles of the pathway in many cellular and tissue *** it has critical roles in regulating cell proliferation,differentiation,apoptosis,and ***,the impact ofβ-catenin activation on life span of primary cultured human skin fibroblasts(HSF)are poorly *** investigate the effect of over-expressionβ-catenin on oxidative stress and the expression of p16in UVB-induced premature senescence of HSF.
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